Influences Of Stress And Coping Strategies On Quality Of Life In Patients With Globus

Background:Globus is a kind of debilitating functional gastrointestinal disorders(FGIDs),characterized by the sense of a lump in the throat.It is a commonly encountered condition that is generally extended,recrudescent,and hard to cure.Currently,due to the imprecise pathogen of globus,it remains burdensome to establish standard investigation and treatment for patients.Clinically,it was tougher for medical workers to master the subjective behaviors of globus patients.Thence,this disease damaged patients’ levels of health,which also reduced a lower quality of life.It is well known that all kinds of FGIDs often have similar pathogenesis and related factors that induce or exasperate them.As the bio-medical model developing into bio-psycho-social medical model,more and more attentions were paid to the role of psychosocial factors in disease occurrence and evolution.Nowadays,a great quantity of intellectuals were circumspectly conscious of various stimuli,which was engendered by mental burden and negative events inside and outside,begot dysfunction of brain gut axis by way of stress response.Accordingly,digestive tract had inordinate peristalsis and increased susceptivity,which was the pathogenic mechanism of FGIDs.Among digestive diseases,the correlation of.psychological stress and peptic ulcer disease has been confirmed;and stress is very closely associated with irritable bowel syndrome.As for globus,the influence caused by psychological stress has become eye-catching in recent studies.In population-based survey,almost 96%of globus patients believed that stress events often occurred before the onset of globus,and symptoms would also worsen when stress increased.Stress may be an important cofactor in the occurrence and development of globus symptom.In addition,effective coping strategies can decrease both intense stressors and incessant strains to reduce the adverse aftereffects.Wherefore,it is significant to explore the impact of stress and coping strategies on the quality of life of globus patients in China.Objective:Firstly,this study was committed to explore the relationship between perceived stress,coping strategies and quality of life among globus patients.Secondly,we aimed to further understand the influencing factors of quality of life to provide theoretical guidance for improving the quality of life of globus patients.Methods:This was a cross-sectional study conducted among 180 globus patients,which were in the first affiliated hospital of Zhengzhou University from September 2018 to July 2020.Demographics and clinical characteristics of patients included gender,age,education,marital,monthly income,occupation,course of disease,the number of previous chronic illness,and the severity of sickness.The severity of sickness was appraised by Glasgow Edinburgh Throat Scale(GETS).Quality of life was judged by short form-36 health survey(SF-36),which embodied physical composite score(PCS)and mental composite score(MCS).Perceived stress was measured by perceived stress scale 10(PSS-10).The coping strategy was evaluated by medical coping modes questionnaire(MCMQ).T test,one-way analysis of variance test and Pearson’s correlation analyses were used to analyze the relationship between baseline characteristics,stress,coping strategies,and quality of life.Multiple regression analysis was performed to analyze the influencing factors of quality of life.Results:Consequences of descriptive statistics illustrated that globus patients existed high stress intensity and damaged quality of life.In the subscales of SF-3 6,physical function retained highest average score,however,vitality held lowest score.Results of t test,one-way analysis of variance test,and Pearson correlations manifested that the PCS was affected by the number of previous chronic illness,age,stress,confrontation,and avoidance(F=3.647,r=-0.263,-0.634,0.249,-0.329,all P<0.05).MCS was influenced by monthly income,marital status,stress,confrontation,and resignation(F=1.963,5.764,r=-0.312,0.384,-0.360,all P<0.05).The consequences of multiple linear regression analysis indicated that stress was negatively correlated with both PCS and MCS(t=-3.883,-9.708,all P<0.001),confrontation was positively correlated with both PCS and MCS(t=2.030,2.798,P=0.044,0.006),and resignation was negatively correlated with MCS(t=-1.585,P=0.025).Besides,age was negatively correlated with PCS(t=-2.736,P=0.007),and monthly income was positively correlated with MCS(t=2.497,P=0.013).Conclusions:Quality of life of the globus patients was poor.We found that stress and confrontation coping were significantly correlated with both PCS and MCS in patients.Furthermore,resignation was strongly correlated with poor MCS.Additionally,the quality of life in globus patients was influenced by factors including the number of previous chronic illness,age,monthly income,and marital status.Higher level of stress,more use of resignation as a coping style,and older age,would lead to worse quality of life in patients with globus.Lower level of stress,more use of confrontation,and higher income would lead to better quality of life.