Clinical Observation Of Bloodletting Therapy And External Application Of Qingdai Pastes In Treating Patients With Acute Herpes Zoster With Hepatobiliary Depression And Heat

Objective:The study is to observe the therapeutic effect of bleeding therapy combined with Qingdai Pastes in the treatment of herpes zoster with acute hepatobiliary stagnation and heat type herpes zoster through clinical trials,and to observe its contrast with the conventional treatment.To explore the exact efficacy and clinical safety of herpes zoster.Methods: 1.All the patients in this subject came from November2019～January 2021.All the patients met the inclusion criteria and diagnostic criteria of undergraduate questions.The patients were randomly divided into two groups,trial group and control group,35 people in each group.Patients in 2.trial group were treated with bloodletting therapy,external application of Qingdai Pastes,oral valaciclovir hydrochloride tablets(0.3g bid),Sodium phosphonate cream for external use(bid).3.control group oral valaciclovir hydrochloride tablets(0.3 g bid),Yuantong mixture(50 m L bid),blister rupture and scab site external use of chlortetracycline glycerol(tid),sodium phosphonate cream external use(bid).4.if the patient feels unbearable or VAS≥ 4.Give oral Prebalin capsule(75 mg bid).General score of skin lesions,VAS score,time to stop blister,time to scab,time to fade erythema,whether postherpetic neuralgia,adverse reactions occurred.And accurately fill out the clinical observation form.After collecting the data,the SPSS software 23.0 was used for data processing and statistical analysis,and the difference between the two groups was analyzed.The difference was statistically significant,if P<0.05,The difference is statistically significant.Result:1.Gender and age composition of the two groups were not statistically different,the course of disease,skin lesion score and VAS score of the two groups before treatment were not statistically different,and the test data of the two groups were compared.2.The treatment time of herpes zoster,the time of erythema regression and the time of scab formation in the experimental group was better than that in the control group(P<0.01).3.After treatment,the remission degree of VAS score was better than that of control group(P<0.01).4.After treatment,the patients in the treatment group had a better degree of relief than those in the control group,which was statistically significant(P<0.01).5.One case of postherpetic neuralgia occurred in the follow-up treatment group,and 3 cases of postherpetic neuralgia occurred in the control group,but were statistically analyzed P>0.05,There was no significant difference between the two groups.Therefore,this test can not show that the treatment group in the control of postherpetic neuralgia due to the control group.6.In the treatment group,3 patients complained of mild fear of bleeding therapy,but tolerated,and completed the treatment in sufficient quantity without adverse reactions.There was no adverse reaction in the control group.Conclusion:1.Bleeding therapy combined with Qingdai Pastes external application in the treatment of acute herpes zoster with liver and gallbladder stagnation and heat can effectively improve skin lesions and relieve pain.2.Bleeding therapy combined with external application of Qingdai Pastes combined with oral western medicine is better than oral western medicine in the treatment of acute stage herpes zoster of liver and gallbladder stagnation heat type.3.Bloodletting therapy combined with Qingdai Powder external application in the treatment of acute herpes zoster with liver and gallbladder stagnation and heat type had no obvious adverse reactions and high safety.