| Objective:Based on the factor analysis of multivariate statistical method,the data of four diagnosis information of acute atherosclerotic cerebral infarction collected were excavated,the distribution characteristics of syndromes of traditional Chinese medicine were combed,and the main points of syndrome differentiation were determined.In order to provide theoretical basis for the prevention and treatment of acute atherosclerotic cerebral infarction CISS TCM syndromes.Methods:This study used cross-sectional method to collect the general situation of patients with acute atherosclerotic cerebral infarction who were hospitalized and outpatient in encephalopathy department of Shanxi traditional Chinese Medicine Hospital from May2019 to March 2021.Results:1.General analysis: patients aged 45 to 92,Average age 66.19±11.10 years.The number of male patients accounted for 70.5% of the total,Women account for 29.5 per cent.According to the statistical LAA,the sex difference between the four pathogenesis patients,The difference was not statistically significant.Risk factors :53.8% alcohol consumption,Smoking accounts for 52.6% of the total,Overweight accounts for 45% of the total.There was no significant difference between the four pathogenesis patients under risk factors.41.1% of diabetics,The proportion of patients with hypertension was 68.0%,The number of people who had a history of cerebrovascular disease accounted for 43.6%of the total,The proportion of hyperhomocysteinemia was 12.1%,Hyperlipidemia accounted for 88.7% of patients.Among them,Carrier artery occlusion and perforating artery accounted for 40.2% of patients,Artery to artery 23.4%,The proportion of mixed mechanisms is 22.1 per cent,The clearance rate of low perfusion / embolus was 14.3.2.Four diagnosis information analysis:the frequency of four diagnosis in 435 patients with acute atherosclerotic cerebral infarction is more than 10%: abdominal distention,dry stool,tongue less weight,tongue stasis spot,white fur,greasy fur,less fur,pulse number,heavy pulse,thin pulse,irritable irritability,frequent urination,yellow fur,smooth pulse,swollen limbs,cold,tired spirit,slow pulse,weak pulse,palpitation,sore waist and knee,tinnitus,dark face,yellow face,dry mouth,thirsty drink,stool,fat tongue,thin tongue mark,dizziness,pulse acerbity,constipation,cough,nausea,vomiting,purple mouth,purple tongue,oblique tongue or quiver tongue,abnormal feeling of the body,head and body,heavy mouth,sleepy mouth,string back,bitter Should be dull,self-sweating,dry mouth,tongue light,walking instability,dull,dizzy,salivate,phlegm between the throat,obesity,chest tightness,mouth-eye skew,mouth sticky greasy,thick fur,forgetful,dry,hot hands and feet,head stuffy pain,insomnia,thin fur,tongue red,sputum,limb numbness,limb arrest,night sweat,tongue crack.The first 4 places with the highest frequency of tongue appearance were dark tongue,light tongue,white fur and stasis spots.The first four places of pulse were pulse sink,pulse number,pulse fine,pulse string.3.Factor analysis :435 cases were tested by KMO values,KMO =0.657;After Bartlett sphericality test,Significant 0.000,Explain the suitability of factor analysis.The total variance of applicability analysis factor is about 0.6-0.7,Total cumulative variance contribution rate 69.658%,Be able to fully cover and explain the original variables.For the initial common factor,After 37 iterations of convergence,the rotation factor load matrix is22,f1-f22.named Choose the variable of load coefficient >0.3 in the matrix to sort out.Based on TCM theory and clinical experience,The results were reduced to 6 TCM syndromes: F1: blood stasis syndrome(f1 f2 f7 f18);F2: Yang deficiency syndrome :(f3);F3: Yin deficiency syndrome(f4 f15 f16 f20 f21 f22);F4: Qi deficiency syndrome(f5 f6f10 f12 f17);F5: heat certificate(f8 f9 f14);F6: phlegm dampness syndrome(f11 f13f19).Finally,the standardized data is substituted into the common factor equation,According to the distribution of TCM syndrome factors in 435 patients with acute atherosclerotic cerebral infarction,121 cases of F1 blood stasis syndrome(27.82%),F232cases(7.36%)of deficiency syndrome,F3 of 107 cases of Yin deficiency syndrome(24.60%),F4 of 94 cases of Qi deficiency syndrome(21.61%),28 cases of F5 fever(6.44%),F653 cases of phlegm dampness syndrome(12.18%),The highest frequency of the first 3 syndrome factors are: blood stasis syndrome,Yin deficiency syndrome,Qi deficiency syndrome.Conclusion:Through the clinical information analysis of TCM,LAA syndrome is mainly in liver,spleen,kidney,heart,blood stasis,Yin deficiency,gas deficiency,phlegm deficiency,wet,Yang deficiency and heat,the most common factors of LAA patients are blood stasis,followed by Yin deficiency,gas deficiency,phlegm dampness,Yang deficiency and hot syndrome.After analysis,most of the LAA patients is due to blood stasis,blood stasis,blood stasis,stasis meridians,or Yin deficiency of viscera liver and kidney,or Qi and blood biochemical deficiency,loss,Bi meridians,in addition,such as phlegm damp block,Yang deficiency inability to promote or liver Yang wind and other pathological factors,through external evil injury,Yin and Yang disorders,Qi and blood disorder,disease.When we are in the clinical diagnosis and treatment of LAA patients,we should focus on the products of promoting blood circulation and removing blood stasis,nourishing Yin and latent Yang,replenishing qi,clearing dampness and phlegm,warming Yang and helping transportation,clearing heat and clearing heat and removing fire.Blood stasis certificate can be used as the focus of the treatment of LAA patients,pay attention to strengthen the use of promoting blood circulation and blood stasis,more likely to make the curative effect of patients;also,more attention should be paid to strengthening nourishing Yin and replenishing qi,strengthening the treatment.Through the study,we know that using factor analysis is feasible to study the syndrome distribution of LAA patients,so as to provide a basic basis for clinical syndrome differentiation and diagnosis and treatment. |
PDF Full Text Request