The Analysis Of Detection Time Of Neonatal Automatic Auditory Brainstem Response On The Passing Rate Of Primary Screening And Its Influencing Factors

Objective:To explore the influence of the detection time of neonatal automatic auditory brainstem response(AABR)on the passing rate of primary screening and the analysis of the factors affecting the detection time.Methods:In this retrospective study,472 neonates in neonatal intensive care unit(NICU)were selected as the study group and 182 normal neonates as the healthy control group.The neonates in the two groups were screened by MAICOMB11 automatic auditory brainstem response test.1.The AABR passing rate of newborns at different testing times was recorded,and the influence of the first AABR testing time on the test results of the two groups of newborns was evaluated;2.Analyze the influencing factors of AABR detection time for NICU newborn.Results:1.The failure rates of the study group with AABR detection time of 180s,360s and 540s were 41.5%,28.4%and 24.4%,respectively,while those of the healthy control group were 31.3%,19.8%and 15.4%,respectively,gradually decreases with the extension of detection time(P<0.05);2.Kappa consistency test was conducted for the pass rates of different detection times,and the results showed that the detection results of 180s,360s and 540s in the two groups were generally consistent(Kappa<0.75,P<0.05),and the detection results of 360s and 540s were better consistent(Kappa>0.75,P<0.05);3.Survival analysis was used to analyze the duration of aural detection in the two groups.The median duration of AABR detection in the study group was 108s(95%CI:97-120s),longer than that in the healthy control group(75s,95%CI:65-85s)(P<0.05).Cox regression analysis showed that the risk factors for prolongation of AABR testing time included maternal age≥35 years,anemia,electrolyte disturbance(RR<1,P<0.05),and prolonged duration of continuous positive airway pressure assisted breathing was a protective factor(RR>1,P<0.05).Conclusions:1.Extending the AABR primary screening time to 360-540s helps to reduce the false positive results caused by environmental factors and risk factors;2.Timely intervention for NICU newborns with high risk factors may help to reduce false positive results of A ABR screening before discharge.