| BackgroundCervical cancer is a kind of common malignant tumor in disease of female reproduction system,general onset age is in 20 years old ～80 years old,with 50 years old～55 years old for high hair age.In recent years,the incidence of the disease tends to be younger.Cervical cancer is a long process.According to the 2018 FIGO staging standard,IA2-IIA is an early stage of cervical cancer,which can be cured with appropriate treatment.With the continuous maturation of minimally invasive techniques,many literatures have shown that laparoscopic radical surgery has some advantages in the treatment of early cervical cancer compared with open radical surgery.However,whether laparoscopic surgery can achieve the same effect as laparotomy in terms of intraoperative,postoperative complications and postoperative sexual life needs to be further studied.In addition,there are few clinical studies on the effects of laparoscopic surgery and laparotomy on postoperative sexual life.Therefore,this study took the clinical data of cervical cancer patients admitted to our hospital who underwent laparoscopy and laparotomy radical surgery as the object of study,and compared and analyzed the intraoperative and postoperative related indicators of the two types of surgery,in order to explore the effectiveness and safety of laparoscopic surgery,and to provide a basis for clinical selection of appropriate surgery.ObjectiveIn order to explore the effectiveness and safety of laparoscopic surgery and laparotomy in the treatment of early cervical cancer,To explore the advantages and disadvantages of laparoscopy and laparotomy in the treatment of early cervical cancer andtheir effects on sexual life.Method126 cases of early cervical cancer patients admitted to puyang people’s hospital from January 2015 to January 2018 were retrospectively analyzed and postoperative follow-up was conducted,and postoperative inflammatory response indicators were analyzed.Patients undergoing laparoscopic surgery served as the observation group(n=66),and patients undergoing laparotomy served as the control group(n=60).Intraoperative blood loss,number of lymph node dissection,operation time,postoperative exhaust time,catheter extraction time,operation time,postoperative complications(urinary retention,intestinal obstruction,lymph node retention cyst,lower limb venous thrombosis,wound infection,poor wound healing,etc.)and hospital expenses were recorded in the two groups.During postoperative follow-up,Female Sexual Function Index(FSFI)was used to evaluate the Sexual quality of patients at 6 and 12 months after surgery.Results1.The levels of TNF-α,IL-6,CRP,WBC and NEUT were all increased to different degrees in the two groups 1 and 3 days after the operation.1d and 3d after the operation,serum TNF-α,IL-6,and CRP levels in the observation group were significantly lower than those in the control group at the same time(P <0.05).2.The operation time,catheter extubation time and hospitalization cost in the observation group were significantly higher than those in the control group,and the number of blood transfusion cases,intraoperative blood loss,postoperative exhaust time and hospitalization time in the observation group were significantly lower than those in the control group,the differences were statistically significant(P <0.05).3.The incidence of complications in the observation group(3.03%)was significantly lower than that in the control group(13.33%),and the difference was statistically significant(P <0.05).4.During the follow-up at 6 months,the scores of sexual arousal,orgasm,vaginal lubrication and sexual satisfaction in the observation group were significantly higher than those in the control group,the differences were statistically significant(P<0.05).The total FSFI score in the observation group was significantly higher than that in the control group(P<0.05).The incidence of sexual dysfunction in the observation group(37.88%)was significantly lower than that in the control group(70.00%),P<0.05.5.During the 12-month follow-up,the incidence of sexual arousal,sexual desire,orgasm,vaginal lubrication,pain during intercourse,sexual satisfaction score,FSFI general evaluation and sexual dysfunction in the observation group were compared with the control group,respectively,the difference was not statistically significant(P>0.05).Conclusion1.Compared with laparotomy,laparoscopic surgery has less trauma and faster postoperative recovery,which can reduce the incidence of complications and shorten the length of hospital stay.2.For cervical cancer patients,both of the two surgeries affected the patients’ sexual life quality,but the influence on sexual life quality was more serious within 6 months after laparotomy.at 12 months,the sexual life quality of both patients improved,but the difference was not significant. |
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