Correlation Between Carotid Intima-media Thickness And Constitution Of Traditional Chinese Medicine In Essential Hypertension

Obiective:Through the analysis of the risk factors and clinical indicators of the patients with essential hypertension and carotid intima-media thickening,to explore the correlation between the disease and the constitution of traditional Chinese medicine,in order to reduce the incidence of cardiovascular and cerebrovascular diseases by early intervention of the susceptible constitution of hypertension arteriosclerosis.Methods:292 cases of essential hypertension with carotid artery intima-media thickening were included in the study.According to Professor Wang Qi’s classification of traditional Chinese medicine constitution,the physique was identified,the data collection was completed,the relationship between each index and physique type was statistically analyzed,and the analysis and summary were made with the help of statistical technology.Results:1.In the distribution of constitution types of patients with essential hypertension and carotid intima-media thickening,161(55.14%)had single constitution and 131(44.86%)had mixed constitution,among which phlegm dampness(13.70%),damp heat(12.67%),phlegm dampness and blood stasis(9.25%)accounted for the largest proportion.2.In the distribution of constitution types,the first grade of hypertension is mainly composed of phlegm dampness,damp heat and Qi deficiency,the second grade is mainly composed of phlegm dampness,damp heat and phlegm dampness and blood stasis,the third grade is mainly composed of blood stasis,damp heat and Qi deficiency;the thickness of carotid intima-media is mainly composed of phlegm dampness,phlegm dampness and blood stasis,and the plaque is mainly composed of the thickening of intima-media The formation is mainly phlegm dampness and heat dampness.3.In this study,the correlation of gender,age and Constitution:in gender,the number of male patients with phlegm dampness,damp heat,phlegm dampness and blood stasis is the largest(40.00%),and the number of female patients with phlegm dampness,damp heat,blood stasis,phlegm dampness and blood stasis is the largest(41.21%).In terms of age composition,the youth mainly have the quality of qi deficiency and phlegm dampness,Qi deficiency and damp heat(43.47%),the middle-aged mainly have the quality of damp heat,phlegm dampness,Qi deficiency and blood stasis(41.87%),the old mainly have the quality of phlegm dampness,damp heat,phlegm dampness and blood stasis(35.52%).4.Correlation between constitution and examination indexes of hypertension patients with carotid artery intima-media thickening:phlegm dampness is related to the increase of glycosylated hemoglobin and homocysteine;damp heat,Qi deficiency and blood stasis are related to the increase of C-reactive protein;history of cerebral infarction is related to blood stasis.Conclusion:1.The proportion of phlegm dampness,damp heat,phlegm dampness and blood stasis is the largest in patients with essential hypertension and carotid intima-media thickening,which suggests that these three constitution are the main susceptible constitution of the disease.2.The relationship between the classification of hypertension,the thickness of carotid intima-media and the type of Constitution: the first and second grades of hypertension are mainly composed of phlegm dampness and heat dampness,the third grade of hypertension is mainly composed of blood stasis and heat dampness;with the increase of carotid intima-media thickness,the proportion of heat dampness is increasing.3.The relationship between age,gender and constitution type in patients with essential hypertension and carotid artery intima-media thickening: the proportion of blood stasis in female patients is significantly higher than that in male patients;from youth to old age,damp heat is the susceptible constitution in all age stages.On this basis,the Qi deficiency of young patients is more obvious,and the phlegm dampness of middle-aged and old patients is more obvious.4.The correlation between physical fitness and examination indexes in patients with hypertension and carotid intima-media thickening:when glycosylated hemoglobin and homocysteine are increased,the patients with phlegm dampness are more likely to suffer from the disease;when C-reactive protein is increased,the patients with damp heat,Qi deficiency and blood stasis are more likely to suffer from the disease;the patients with cerebral infarction history are more likely to suffer from the disease.