Clinical Study On The Treatment Of Chronic Functional Constipation(Liver Depression Type) By Improving Intestinal Flora With Shugan Xingqi Decoction

Objective:To observe the change of intestinal flora and clinical effect of Shugan Xingqi Decoction in the treatment of chronic functional constipation.Methods:According to the needs of clinical research,60 patients with chronic functional constipation(liver depression type)were randomly divided into two groups,30 in the treatment group(self-made liver Qi dispersing Decoction)and 30 in the control group(compound polyethylene glycol electrolyte powder).To observe and record the clinical quantitative evaluation of constipation before and after treatment(stool induration,defecation patency,defecation time,feeling of endless defecation,feeling of anal obstruction,feeling of anal descent,defecation interval,abdominal distention)and the change of intestinal microflora(rod cocci ratio,fecal pH value).The clinical data were summarized and statistically analyzed to evaluate the clinical effect of Shugan Xingqi decoction.Results:There were 57 cases in the study,28 in the treatment group and 29 in the control group.There was no significant difference between the two groups in the basic clinical data before treatment(P>0.05).1.Comparison of the overall effect of the two groups:the total effective rate of the treatment group was 89.29%,the total effective rate of the control group was 62.07%,the overall effect of the treatment group was better than that of the control group(P<0.05)2.Comparison between the two groups before and after treatment:after treatment,the clinical quantitative evaluation of constipation and the change of intestinal flora in the two groups were significantly improved(P<0.05).3.Comparison between the two groups after treatment:in terms of clinical quantitative evaluation of constipation,the improvement of defecation time(min/time)and defecation interval(day/time)in the treatment group was significantly better than that in the control group(P<0.05).In the aspect of intestinal flora change,the treatment group was better than the control group in the proportion improvement of Gram-positive bacteria,Gram-negative bacteria and gram-negative cocci(P<0.05),and there was no significant statistical difference in the proportion improvement of Staph and gram-positive cocci(P>0.05).The improvement of fecal pH in the treatment group was better than that in the control group(P<0.05).Conclusion:The clinical study shows that the two treatment methods can effectively alleviate the symptoms of chronic functional constipation(liver depression type);compared with Shutai Qing,Shugan Xingqi decoction has the following advantages:overall efficacy,defecation time(min/time),defecation interval time(day/time),improvement of Gram-positive bacilli,gram-negative bacilli,gram-negative cocci and fecal pH It has good curative effect and no obvious adverse reactions.