The Study Of Improving The Abnormal Metabolism Of Non-alcoholic Fatty Liver Glycolipid By Shuganjianpihuoxuehuatanfa

ObjectiveTo observe the clinical effect of shuganjianpihuoxuehuatanfa in the treatment of non-alcoholic fatty liver disease,to further explore the effect of shuganjianpihuoxuehuatanfa on dyslipidemia and abnormal glucose metabolism in non-alcoholic fatty liver disease.MethodFrom December 2010 to December 2019,the patients with non-alcoholic fatty liver disease in the outpatient and inpatient departments of Guangdong Provincial Hospital of traditional Chinese Medicine were studied.The patients were divided into treatment group and control group,including 101 cases in the treatment group and 92 cases in the control group,with a course of treatment of 24 weeks.ResultsThe baseline comparison between the treatment group and the control group 24 weeks before treatment was not statistically significant(P>0.05),indicating its comparability.After 24 weeks of treatment,the results were as follows:Index of liver function:the alt,ast,ggt in the treatment group after intervention were compared with before treatment.by statistical analysis,P<0.05,the difference was statistically significant.ALT,AST,GGT in the control group after treatment compared with before treatment,through statistical analysis,P>0.05,the difference was not statistically significant.after intervention,the contrast between the two groups:alt,ast,ggt of the two groups after treatment,through statistical analysis,P<0.05,the difference was statistically significant.indicating that the treatment group was superior to the control group in improving liver function.Fasting blood glucose index:fasting blood glucose in the treatment group after intervention was compared with before treatment,through statistical analysis,P<0.05,the difference was statistically significant.The fasting blood glucose of the control group was compared with that before treatment after treatment,and by statistical analysis,P>0.05,the difference was not statistically significant.After intervention,the two groups were compared:fasting blood glucose in the two groups after treatment,through statistical analysis,P<0.05,the difference was statistically significant.indicating that the treatment group was superior to the control group in improving fasting blood glucose.Blood lipid levels and bmi:triglycerides,cholesterol,ldl,bmi in the treated group after intervention were compared with pre-treatment after treatment.through statistical analysis,P<0.05,the difference was statistically significant,while high-density lipoprotein,by statistical analysis,P>0.05,the difference was not statistically significant.The blood lipid levels of the control group were compared with those before treatment after treatment,and by statistical analysis,P>0.05,the difference was not statistically significant.BMI was compared with that before treatment after treatment,and by statistical analysis,P<0.05.The difference was statistically significant.after intervention,the two groups were compared:triglyceride,cholesterol,ldl,bmi in the two groups after treatment,through statistical analysis,P<0.05,the difference was statistically significant,while high-density lipoprotein,through statistical analysis,P>0.05,the difference was not statistically significant.The results showed that the treatment group was superior to the control group in improving total cholesterol,triglycerides,low-density lipoprotein and BMI,while the two groups had the same effect.Blood uric acid index:After intervention,the blood uric acid in the treatment group was compared with that before treatment,and by statistical analysis,P<0.05,the difference was statistically significant.The blood uric acid in the control group was compared with that before treatment after treatment,and the difference was not statistically significant by statistical analysis,P>0.05.After intervention,the contrast between the two groups:after the treatment of blood uric acid in the two groups,through statistical analysis,P<0.05,the difference was statistically significant.indicating that the treatment group was superior to the control group in improving blood uric acid.Fibroscan indicators:The LSM and CAP values of the treatment group after intervention were compared with those before treatment after treatment,and the difference was statistically significant by statistical analysis of P<0.05.The LSM and CAP values of the control group were compared with those before treatment after treatment,and the difference was not statistically significant by statistical analysis,P>0.05.The comparison between the two groups after intervention:the LSM value and CAP value of the two groups after treatment,through statistical analysis,P<0.05,the difference was statistically significant.indicating that the treatment group was superior to the control group in improving Fibroscan.Total score of TCM syndromes:The total score of TCM syndromes in the intervention treatment group was compared with that before treatment after treatment,and by statistical analysis,P<0.05,the difference was statistically significant.The total score of TCM syndromes in the controlgroup was compared with that before treatment after treatment.Through statistical analysis,P<0.05,the difference was statistically significant.After the intervention,the total score of TCM syndromes in the two groups was treated,through statistical analysis,P<0.05,the difference was statistically significant.Comprehensive curative effect analysis:in the aspect of comprehensivecurative effect,the effective rate of the treatment group was 99.00%,and the effective rate of the control group was 61.95%.After statistical analysis,P<0.05,there was a statistical difference.ConclusionFor liver enzyme index,blood lipid level,fasting blood glucose and blood uric acid,liver function,blood lipid,fasting blood glucose and blood uric acid were better than those in control group.