A Retrospective Analysis Of 218 Cases Of Varicocele Infertility

ObjectiveTo observe the recovery of semen parameters in varicocele infertility patients after traditional Chinese medicine or surgical treatment,and to explore the influencing factors.MethodsClinical data of patients with varicocele infertility of kidney-qi deficiency and blood stasis treated by Danhong Tongjing Prescription or microsurgery in our hospital from January 2017 to July 2019 were collected to compare the recovery of semen parameters after treatment.Multiple linear regression model was established with age,course of disease,degree of varicocele,change of testicular volume,ratio of estrogen to testosterone,FSH and LH as the independent variables,and the increment of semen parameters after treatment as the dependent variables.ResultsA total of 218 cases were collected,including 86 in the traditional chinese medcine(TOM group and 132 in the operation group.After 1.5-3 months of danhongtong jing prescription,the sperm concentration,percentage of forward motile sperm and percentage of normal sperm were significantly different in the TCM group than before treatment.Sperm concentration,percentage of forward motility sperm and percentage of normal morphology sperm in the microsurgical group improved significantly after surgical treatment,and the difference was statistically significant.Between Chinese medicine group and surgery group,the sperm concentration,percentage of forward motility sperm and percentage of normal morphology sperm have no statistical difference after tretment;The difference between the two groups before and after treatment showed that there was a statistical difference in sperm concentration and percentage of normal sperm,but no statistical difference in the percentage of forward motility sperm.The results of linear regression analysis of traditional Chinese medicine group indicated that the degree of varicocele affected the recovery of semen concentration after treatment with traditional Chinese medicine.The higher the degree of varicocele,the less the increment of sperm concentration after treatment.Linear regression analysis of the operation group indicated that the course of varicocele infertility was a negative factor affecting the increase of postoperative sperm count.ConclusionDanhongtongjing prescription for the treatment of varicocele infertility has the same effect on improving effective sperm count as microsurgery.And Surgical treatment was more effective in improving sperm concentration and percentage of normal morphology sperm.Early surgical treatment is recommended for severe varicocele,especially for bilateral moderate or above infertility.For patients with mild bilateral or moderate unilateral varices leading to infertility or hospitals with weak surgical intention and unconditional operation,traditional Chinese medicine treatment can be selected.