| Objective: Eevaluate the effect of moderate-intensity aerobic exercise on blood glucose,body composition and blood pressure in middle-aged and elderly patients with diabetes mellitus and hypertension,and to investigate the effect of different exercise frequency on glucose and lipid metabolism in patients with diabetes mellitus and hypertension.Methods: 62 patients between 50 and 69 years of age with or without confirmed hypertension(systolic blood pressure 130-159 mm Hg and/or diastolic blood pressure85-100mmhg)with type 2 diabetes were recruited from two neighborhoods in Haidian district,Beijing.(1)cross-sectional study: the blood glucose,blood lipid and body composition of 22 patients with simple diabetes(9 males and 13 females,mean age: 61.00±7.79 years old)and 40 patients with diabetes and hypertension(15 males and 25 females,mean age: 62.95±5.94 years old)were analyzed.(2)exercise intervention: the two groups of diabetic patients in the cross-sectional study were randomly selected to walk at a moderate intensity for a period of 3 months according to the principle of voluntary participation,and the effects of exercise intervention and the differences in different exercise frequencies were observed.T test and analysis of variance were used for baseline data and test data before and after exercise intervention,and P < 0.05/0.01 was regarded as significant/very significant difference.Results: 1.Cross-sectional results: the difference of systolic blood pressure and pulse pressure in diabetic patients with hypertension was significantly higher than that in diabetic patients(P < 0.05).BMI,body fat rate and visceral fat content in diabetic patients with hypertension were significantly higher than those in patients with simple diabetes(P<0.05).Diabetic patients with hypertension also have at least one other chronic disease;Results of 3-month exercise intervention: regular moderate-intensity aerobic exercise can significantly reduce the waist-to-hip ratio(P= 0.045),significantly reduce the systolic blood pressure(P= 0.024),significantly improve the vasodilation function(P= 0.045)and the level of a1 c hemoglobin(P= 0.002)in diabetic patients with hypertension,and significantly increase the level of HDL cholesterol in diabetic patients with hypertension(P=0.025).The serum triglyceride level of the patients with complications who exercised more than 4 times a week on average and walked with moderate intensity decreased significantly(P=0.039,P <0.01).Systolic blood pressure recovered more quickly in diabetic patients with hypertension after exercise,but there was a significant difference in the rate of decline before and after exercise(P<0.05).Conclusion: 3 months of regular moderate intensity walking had no significant effect on hba1 c level,blood glucose and body composition in diabetic patients,and significantly reduced waist-to-hip ratio in diabetic patients.Significantly reduced systolic blood pressure in patients with diabetes and hypertension,significantly improved vasodilation,HDL cholesterol,and hba1 c in patients with hypertension.In patients with diabetes mellitus and hypertension,increasing the number of exercise times per week can significantly reduce the triglyceride level,reduce the glycosylated hemoglobin level,and improve the control of blood glucose. |