| Objective:Through the investigations of epidemiology and informations of bile reflux gastritis,a database was established,and multivariate statistical methods were used to analyze the related factors of the disease,and the syndrome pattern and syndrome distribution of the disease were explored to provide evidence for the syndrome differentiation and treatment of the disease.Reference basis,and promote the standardization and objectification of TCM syndrome differentiation.Methods:Through the review of book literature,guidelines and consulting experts,the "Clinical Observation Scale for Bile Reflux Gastritis" was developed.From February 2017 to December 1818,200 cases of spleen and stomach disease in the Affiliated Hospital of Shandong University of Traditional Chinese Medicine met the inclusion criteria.The patient conducted a questionnaire to collect general information and four diagnostic information.Using Excel and SPSS21.0 statistical software to analyze the patient’s age,gender,body mass index,occupation,education,lifestyle,Helicobacter pylori infection,anxiety and depression,and systematic cluster analysis and factor analysis of the main four diagnostic information.In combination with "syndrome differentiation syndrome",the rules of syndrome type and syndrome elements are discussedResults1.General information:The incidence of this disease was mainly 40-49 years old,and the majority of womenhad the highest body mass index.In terms of occupational distribution,There were more teachers,senior self-employed personnel and staff.In terms of education,the incidence of high school education was higher;the degree of bile reflux was mainly grade Ⅰ and Ⅱ.The pyloric screw infection rate accounted for 69%of the total number;in terms of emotion,the incidence of anxiety and depression in BRG was extremely high,accounting for 86.5%of the total number,of which BEG had the highest proportion of anxiety and depression.45.09%of the patients with BRG anxiety and depression,followed by BRG with anxiety status,32.95%,and BRG with depression status of 21.97%;different age groups of anxiety and depression were different:20-29 years old,BRG with anxiety ratio High;30-39 years old,BRG with anxiety status,BRG with anxiety and depression status ratio;40-49 years old,50-59 years old,BRG with the highest proportion of anxiety and depression;60-69 years old,70 years old or older,BRG has the highest proportion of depression.Whether it is infected with Helicobacter pylori,the anxiety and depression status of different populations are different:BRG with anxiety status,BRG with anxiety and depression status in Helicobacter pylori-infected population;and for non-Helicobacter pylori-infected people,the most distributed is BRG with anxiety and depression The state group,followed by the normal mental state2.TCM syndrome:The top 10 of the four diagnostic information are:mouth bitterness,stomach cramps,pulse string,pantothenic acid,dry mouth,belching,stomach cramps,red tongue,poor appetite,nausea;Cluster analysis,the main symptoms of BRG patients were clustered into liver-like stagnation,liver-like gas,cold and heat,spleen-deficiency,spleen-like spleen,spleen and stomach qi deficiency;The factor load matrix,and refer to Professor Zhu Wenfeng’s " syndrome differentiation syndrome" in the "syndrome syndrome syndrome scale" to obtain the BRG disease syndrome has stomach,hepatobiliary,heart,spleen;disease syndrome is hot,Qi stagnation,wet,phlegm,yang deficiency.Conclusions1.Anxiety and depression are important factors leading to bile reflux gastritis.2.Bile reflux gastritis is located in the stomach,and is closely related to hepatobiliary,heart and spleen;the disease is divided into virtual and real.The virtual person can see yang deficiency and qi deficiency.In fact,qi stagnation,heat,dampness,phlegm and cold can be seen.It is a common clinical type of liver and stomach stagnation,liver-like gas,cold and heat,spleen and dampness,sputum internal resistance,and spleen and stomach qi deficiency. |
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