Efficacy Evaluation And Safety Evaluation Of Ginseng Bufei Decoction In The Treatment Of Pulmonary Heart Disease With Pulmonary-kidney-qi Deficiency

Objective:Explore the clinical efficacy of ginseng Bufei Decoction on pulmonary-kidney-qi deficiency syndrome of pulmonary heart disease and evaluate its treatment safety.Method:A total of 80 patients with pulmonary-kidney-qi deficiency pulmonary heart disease who were hospitalized in Linyi County Chinese Medicine Hospital from January 2018 to December 2018 were randomly divided into treatment group and control group according to random number table method.In the group of 40 cases,the treatment group was given conventional treatment with Western medicine,and the low-flow oxygen inhalation,antispasmodic and anti-asthmatic,and phlegm-removing were mainly given.Diuretic and vasodilating were given according to the specific conditions of the patients.Antibiotics were added when the infection was combined.In the control group,ginseng supplemented lung drink was added on the basis of routine treatment of western medicine.The treatment period was 2 weeks.The blood gas analysis,pulmonary artery mean pressure,coagulation four,6 min walking test,TCM syndrome scores,and comprehensive evaluation of clinical evaluation were compared between the two groups.Efficacy and treatment safety.Results:1.Before treatment,there was no significant difference in the general data of age,gender and course of disease between the treatment group and the control group(P>0.05).There was no significant difference in the basic vital signs(P>0.05).The blood gas analysis before treatment in the two groups.There was no significant difference in pulmonary artery pressure and 6-min walk test.There was no statistically significant difference in data(P>0.05).There was no significant difference in TCM syndrome scores(P>0.05).The overall study was comparable.2.After treatment,the blood gas analysis,pulmonary artery pressure index and coagulation function of the two groups were better than before,and the distance of 6min walking test was significantly prolonged.The data between the groups and the groups were statistically significant(P＜0.05).The treatment group was better than the control group.group.After treatment,the TCM syndrome scores of the two groups were improved,and the data between the groups and the groups were statistically significant(P＜0.05).The treatment group was superior to the control group.After treatment,the clinical efficacy of the treatment group was better than the control group,the data were statistically significant(P＜0.05),the TCM syndrome efficacy analysis was better than the control group,the data were statistically significant(P＜0.05).3.Safety evaluation,there was no significant difference in the incidence of adverse reactions between the observation group and the control group(5.26%vs 10.81%).There was no significant abnormality in liver and kidney function after treatment in the two groups.There were no statistics between groups and within the group.Learning differences(P＞0.05).Conclusion:Ginseng Bufei Decoction can effectively improve the clinical discomfort symptoms of patients with pulmonary heart disease and lung-kidney Qi deficiency syndrome.Its clinical efficacy is remarkable,especially in reducing pulmonary artery pressure,improving blood gas analysis results and coagulation function,and increasing activity endurance.Ginseng Bufei Decoction can effectively improve the symptoms of cough,cough and asthma in patients with pulmonary heart disease,lung-kidney Qi deficiency syndrome,and improve the score of TCM symptoms.It is safe to treat,and it is worthy of clinical promotion and application in the future.