| Objective:To explore the risk factors of death in patients with acute diquat poisoning and to provide scientific basis for further improving the diagnosis and treatment of diquat poisoning.Methods:The clinical data of 71 patients with acute diquat poisoning admitted to the emergency department of Department of Emergency,Shengjing Hospital,China Medical Universityhospital from June 2015 to September 2020 were retrospectively analyzed,and the clinical data of the patients were recorded in detail.According to the follow-up results,the patients were divided into survival group and death group.The general data and test results of the two groups were compared.Logistic regression method was used to conduct multivariate analysis of death risk of patients with acute dioxin poisoning,and the efficacy of death prediction was evaluated by ROC curve.Results:All 71 patients were included in the study,including 46 males and 25 females,with an average of(41.25±15.78)years old.Among them,46 were in the survival group(64%),25 were in the death group(36%),and the mortality rate was 36%.The single factors affecting the death of patients with acute dioxin poisoning were drug dose,urinary diquat concentration,creatinine(SCR),Urea nitrogen(Urea),aspartate aminotransferase(AST),SIRS score,and Apache II score,with statistical significance(P < 0.05).Sex,age,medication time,WBC,prothrombin time(PT),D dimer(DD),troponin I(TNI),arterial oxygen partial pressure,actual blood bicarbonate,lactic acid(LAC),etc.,had no significant differences between the two groups(P>0.05).Multivariate Logistic regression analysis showed that drug dose,urinary DQ concentration,SCR value,and Apache II score were the risk factors of death in patients with acute diquat poisoning(P<0.05).Conclusion: The mortality rate of patients with acute diquat poisoning is high.Drug dose,urinary diquat concentration,SCR value,and Apache II score are risk factors for death of patients with acute diquat poisoning,and Apache II score can help clinicians predict prognosis of patients with diquat poisoning more accurately. |