Analysis Of Clinical Characteristics Of 3333 Patients With Upper Gastrointestinal Bleeding

Objective To clarify the clinical characteristics of UGIB patients in the recent 10 years,in order to improve the rapid etiological diagnosis rate,reduce the risk of bleeding and mortality.Methods A retrospective cohort study was conducted on 3333 patients diagnosed with UGIB in the Department of Gastroenterology,General Hospital of Ningxia Medical University from January 1996 to December 2005(the first decade)and from January 2011 to December 2020(the second decade).Complete clinical data were included,and the clinical characteristics of UGIB were statistically analyzed using SPSS22.0 statistical software and chi-square test.Results1.Comparing between 1996-2005 and 2011-2020,the primary cause of UGIB was still PU,which was consistent with the epidemiological reports in China,but the etiological composition ratio changed.The proportion of peptic ulcer decreased.The bleeding rate of DU(29.5% vs.25.3%,P < 0.05)and GU(24.6% vs.14.1%,P< 0.01)decreased,and the difference was statistically significant.The proportion of EGV increased(8.7% vs.33.8%,P<0.01),and the difference was statistically significant.The other causes of UGIB from 2011 to2020 were AGML(9.6%),MWS(4.8%)and GC(4.4%).Compared with the previous ten years,the composition ratio of MWS increased(P<0.05),but AGML decreased.The differences were statistically significant,while the composition ratio of GC decreased,the difference was not statistically significant.2.The incidence of UGIB was mainly in winter,spring and autumn.The incidence of EGV hemorrhage increased in spring(P< 0.05)and decreased in autumn(P< 0.01).The rate of GU bleeding was increased in the elderly group(P< 0.01).The rate of DU bleeding was decreased in the young group(P< 0.05).The proportion of EGV bleeding increased in the middle age group(P< 0.05).There was no significant change in the sex composition ratio before and after UGIB(P>0.05).Conclusion1.In the past ten years,the main cause of upper gastrointestinal bleeding was PU,but the composition ratio decreased,EGV and MWS increased,and there was no significant change in GC.2.The incidence of UGIB was related to age and season,but not gender.The incidence of UGIB caused by GU increased with age,while the incidence of DU decreased.UGIB was more common in winter,spring and autumn,while EGV was more common in winter and spring.