Preliminary Study Of Double-layer Detector Spectral CT In Distinguishing Benign And Malignant Vertebral Compression Fractures

Objective:To investigate the value of double-layer detector spectral CT in the differential diagnosis of benign and malignant vertebral compression fractures.Methods:A retrospective analysis of 43 patients with osteoporotic vertebral compression fractures and osteolytic metastatic vertebral compression fractures confirmed by pathology or clinically diagnosed were divided into two groups,benign and malignant,and dual-energy spectral CT was performed.Scan to calculate the CT value at 120 k Vp mixed energy,40-100 ke V and 200 ke V single energy in the region of interest,the K value of the spectral curve slope and the effective atomic number Z value.The Mann Whitney U test and ROC curve were used to compare the difference of the two groups of data and the differential diagnosis power.Results:In the benign group,the CT value,K value and Z value of 40-60 Ke V single energy were higher than those of the malignant group(P<0.05),while the conventional 120 k Vp mixed energy and 70-100 Ke V,200 Ke V single energy CT values had no significant difference(P>0.05).The ROC curve results show that the area under the curve(AUC)of the effective atomic number Z value is the largest,0.887(critical value: 7.85),the slope K value and 40 Ke V single energy CT value have higher diagnostic efficiency.The effective atomic number Z value is higher than 7.85,they are more inclined to osteoporotic vertebral compression fractures.Conclusion:Dual-energy CT has certain application value in distinguishing benign and malignant vertebral compression fractures.