Analysis Of Related Risk Factors For Cerebral Infarction After Vascular Reconstruction In Adults With Moyamoya Disease

Objective:Analyze the risk factors of adult moyamoya disease patients,and provide a basis for the prediction and management of cerebral infarction after vascular reconstruction in adults with moyamoya disease.Methods:This study retrospectively analyzed the clinical case data of 131 adult patients with moyamoya disease who underwent vascular reconstruction at the Second Affiliated Hospital of Nanchang University from September 2018 to March 2021.Among them,there were a total of patients with moyamoya disease who had cerebral infarction after surgery.16 cases(positive group),including 115 patients with moyamoya disease without cerebral infarction after operation(negative group);the gender,age,drinking history,smoking history,hypertension,diabetes,hyperlipidemia,Suzuki staging on the operative side,suzuki staging on the non-surgical side,whether there was a TIA attack in the past 1 month before the operation,whether there was a cerebral infarction before the operation,whether the posterior cerebral artery was involved,and other related factors were analyzed by univariate and multivariate regression analysis to obtain adult smog related risk factors for new cerebral infarction after cerebrovascular reconstruction in patients with the disease.Results:1.The results of univariate analysis indicated that the surgical side suzuki staging,the non-surgical side suzuki staging,the occurrence of TIA in the past 1month before the operation,the cerebral infarction before the operation and the posterior cerebral artery involvement and the differences were compared between the positive group and the negative group.There is statistical significance(P<0.05).2.The results of multivariate analysis indicated that preoperative cerebral infarction and posterior cerebral artery involvement were independent risk factors for postoperative new cerebral infarction(P<0.05).Conclusion:Preoperative history of cerebral infarction and posterior cerebral artery involvement are independent risk factors for cerebral infarction in adult patients with moyamoya disease after revascularization.Patients with moyamoya disease who have had cerebral infarction and posterior cerebral artery involvement before surgery should be closely monitored.Assess,speculate on the risk of cerebral infarction after surgery,and make a prospective decision on whether to adopt vascular reconstruction.