Prevalence Of Osteoporosis And Its Related Factors In Certain Areas Of Community-based Residents In Jilin Province

As the aging of the population accelerates,the prevalence of age-related osteoporosis has increased,which has become a major public health problem playing a part in affecting the health of middle-aged and elderly people,especially postmenopausal women.Because it is a complex disease that is affected by multiple risk factors,it is necessary to more accurately assess the risk of such diseases,and then screen out relevant influencing factors for early prevention and reduce the incidence of disease.Objective:The aims of this study were to obtain the prevalence and distribution characteristics of primary osteoporosis in Jilin Province by collecting population data in certain places in Jilin Province,and clarifying the main influencing factors of primary osteoporosis in Jilin Province,so as to provide corresponding prevention and treatment basis and reference measures for the population in this area,and improving the quality of life of the population.Method:The data of this study is derived from the 2018 Epidemiological Survey of Osteoporosis in Jilin Province.The survey time was from January 2017 to April 2018.Multi-stage cluster stratified sampling was used and four samples of Jilin Province were selected.The survey was carried out in areas,including urban areas: Nanguan District of Changchun and Longshan District of Liaoyuan,and suburban areas: Yushu District of Changchun and Tongyu District of Baicheng.The included population was voluntarily participating residents who were ≥40 years old,had complete bone density testing data and lived in this area for more than 6 months,and excluded the use of anti-osteoporosis drugs and various diseases and drugs that affect bone metabolism.Using the electronic questionnaire uniformly produced by the National Chronic Disease Center,the general demographic characteristics were obtained through Pad questionnaire,living habits,past history of fragility fractures,parental fracture history,and gynecological history of the study population.Height,weight,waist circumference,blood pressure were obtained by body measurement.Laboratory test data included blood glucose and four items of blood lipids,and the bone density was obtained by Dual energy X-ray Absorptiometry.The SPSS 24.0 software was used for statistical description and analysis.At first,the primary osteoporosis-related variables were subjected to a one-way chi-square test,and then all the factors with statistical significance were included in the logistic regression model to research the relationship between each influencing factor and osteoporosis.Results:1.This study included a total of 1,517 individuals,with an average age of 55.92 years.There were 702 males,accounting for 46.28% of the study population,and 815 females,accounting for 53.72% of the study population.2.In this study,there were 318 individuals with primary osteoporosis,with a prevalence rate of 20.96%;there was statistically significant difference in the prevalence between genders(P<0.001),and the prevalence rate of females was significantly higher than males.The prevalence rate of males were 9.40% and the prevalence rate of females were 30.92%;The prevalence of primary osteoporosis increases with age increasing(P<0.001),and the prevalence rate of osteoporosis in40-49 years old was 10.49%,the prevalence rate in aged 50-64 was 21.49%,and the prevalence rate for people over 65 years old was 34.88%;the prevalence rate in urban areas is higher than that in suburban counties(P<0.001),and the prevalence rate in urban areas was 26.22%.County was 15.96%;retired and unemployed people,especially females,were high-risk groups for primary osteoporosis.The prevalence of overweight and obese people was lower than that of normal-weight people,while the prevalence rate of underweight individuals was higher(52.00%).3.Univariate analysis found that age,sex,occupation,residence,body mass index,waist circumference,smoking history,daily exercise time,daily sleep time,parental osteoporosis diagnosis history,pork consumption frequency,cattle,sheep and other livestock consumption frequency,chickens,ducks and geese poultry meat consumption frequency,soy products consumption frequency,milk consumption frequency,tea consumption frequency,diastolic blood pressure,high-density lipoprotein cholesterol,fasting blood glucose were statistically associated with primary osteoporosis(P<0.05).The univariate results in males showed that the influence of body mass index,parental osteoporosis diagnosis history,and high-density lipoprotein cholesterol was statistically significant on the prevalence(P<0.05).The univariate results in females showed age,occupation,residence,body mass index,daily exercise duration,daily sleep duration,fasting blood glucose,pork consumption frequency,chicken,duck and goose and other poultry meat consumption frequency,soy products consumption frequency,high-density lipoprotein cholesterol,menopausal status and menarche age of females was statistically significant on the prevalence of osteoporosis(P<0.05).4.Multivariate results showed that age,gender,occupation,body mass index,pork and soy products consumption,and high-density lipoprotein cholesterol were all influential factors for primary osteoporosis.Increasing age,females(OR=3.688,95%CI:2.599-5.231),retired(OR=5.301,95%CI:1.588-17.702)and unemployed persons(OR=4.280,95%CI : 1.255-14.602),underweight(OR=3.948,95%CI :2.003-7.779),and elevated high-density lipoprotein cholesterol(OR=1.702,95%CI:1.148-2.521)were risk factors for primary osteoporosis.Overweight(OR=0.682,95%CI : 0.496-0.937)and obesity(OR=0.523,95%CI : 0.307-0.892),frequent consumption of pork(OR=0.609,95%CI:0.393-0.944)and occasional consumption of soy products(OR=0.364,95%CI:0.178-0.745)were negative correlation for osteoporosis.The multivariate results in males showed that body mass index and parental osteoporosis diagnosis history were the influencing factors of primary osteoporosis.The multivariate results in females showed age,occupation,body mass index,pork and soy products consumption frequency,fasting blood glucose,high-density lipoprotein cholesterol were influencing factor of female primary osteoporosis.Conclusion:1.Among the 1517 individuals,the prevalence of primary osteoporosis was20.96%,including 9.40% in males and 30.92% in females.The prevalence rate was26.22% in urban areas and 15.96% in suburban counties.2.Age,sex,occupation,body mass index,pork and soy products intake and high-density lipoprotein cholesterol were all influencing factors of primary osteoporosis.3.According to gender stratification,body mass index and the history of osteoporosis of parents were the influencing factors of male primary osteoporosis;Age,sex,occupation,body mass index,pork and soy products intake,fasting blood sugar,and high-density lipoprotein cholesterol were all influencing factors of female primary osteoporosis.