| Objective:To observe the effect of Jinpu gargle on probe periodontal pocket depth(PD),sulcus bleeding index(SBI),fasting plasm glucose(FPG),2-hour postprandial blood glucose(2hPBG)and TCM syndrome score in patients with type 2 diabetes mellitus(T2DM)complicated with chronic periodontitis(CP)with excessive stomach fire,to evaluate its safety and efficacy.Methods:Sixty patients who met the inclusion criteria of diabetes combined with periodontitis and intense stomach fire were randomly divided into an observation group(30 cases)and a control group(30 cases).All patients were given oral health education and basic treatment for diabetes.On this basis,the control group was given the periodontal basic treatment combined with Kangfuxin solution,and the observation group was given the periodontal basic treatment combined with Jinpu gargle.The two groups were treated for 4 weeks.The changes of PD,SBI,FPG,2hPBG and TCM syndrome scores before and after treatment were observed and recorded.Results:There is no significant difference in baseline level between the two groups,which is comparable.(1)Main observation indicators:After treatment,PD and SBI values were significantly decreased in both groups(P<0.05),and PD and SBI values were significantly decreased in the observation group(P<0.05).(2)Secondary observation index:①The curative effect of TCM syndrome:the total effective rate of the control group was 66.67%,and the total effective rate of the observation group was 90.00%,which was significantly better than that of the control group(P<0.05).② TCM syndrome integral:after treatment,by comparing the syndrome integral of the two treatment schemes,the observation group improved significantly in gingival swelling,gingival pain,gingival bleeding and halitosis compared with the control group(P<0.05),but there was no significant difference in the improvement degree of tooth looseness and tongue pulse between the two groups(P>0.05).③ The indexes of glucose metabolism:FPG and 2hPBG in the two groups were decreased after treatment(P<0.05),but there was no significant difference in the improvement degree between the two groups(P>0.05).(3)Safety Observation Index:There was no significant difference in oral health examination scores between the two groups before and after treatment(P>0.05).conclusion:Jinpu gargle can effectively improve the PD,SBI and TCM clinical symptoms in patients with type 2 diabetes(T2DM)combined with chronic periodontitis(CP)and intense stomach fire,with safe and effective. |
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