The Effect Of Timing Of PTGBD Intervention On Elective LC In High-risk Patients With Acute Cholecystitis

Objective:To compare the effect of the timing of PTGBD intervention on the difficulty of elective LC in high-risk patients with acute cholecystitis.Methods:A retrospective analysis was used to collect data from the First Affiliated Hospital of Xinjiang Medical University.Clinical data of patients treated for acute cholestatic PTGBD from January 1,2014 to June 30,2020.There were 30 cases in the early intervention group(≤2 days)and 36 cases in the late intervention group(>2 days).The reasons for tube placement,tube placement-related complications,surgical difficulty,and postoperative pathological findings were compared between the two groups.Results: There were no statistically significant differences between the two groups of clinical patients in terms of age at admission,comorbidities,complications related to tube placement and other basic parameters(P> 0.05).Early group’s operative time(P=0.001),intraoperative blood loss(P=0.017),severe adhesions(P=0.001)and the conversion rate to open(P=0.042)were significantly differences.The Spearman’s correlation coefficient between interval time from onset and conversion was 0.25(P=0.043).Conclusion: PTGBD performed within 2 days of symptom onset may reduce the difficulty of surgery.The conversion in performing LC after PTGBD in patients with acute cholecystitis is positively correlated with the time between performing PTGBD.