Clinical,Morphological And Hemodynamic Characteristics Of Posterior Communicating Artery Aneurysms

Objective: Through collecting the clinical and imaging data of patients with posterior communicating artery aneurysms,the clinical,morphological and hemodynamic characteristics were statistically analyzed to predict the ruopture risk of PcoA aneurysms.To provide the basis for reasonable treatment decision of unruptured posterior communicating artery aneurysm.Methods: Retrospectively analyze the clinical data of 60 patients with posterior communicating artery aneurysms.All the patients are divided into rupture group and unrupture group.The morphological parameters were measured,and the hemodynamic parameters were calculated by the method of computational fluid dynamics.Results: there was no significant difference in the baseline clinical data such as gender,age,history of hypertension,history of diabetes,history of smoking,history of drinking between the two groups(P > 0.05).The size of the ruptured group was significantly larger than that of the unruptured group,and the result was statistically significant(P= 0.002).The aspect ratio,size ratio,dome to neck ratio,bottle neck ratio and inflow angle of the unruptured aneurysms in the unruptured group were higher than those in the ruptured group,and the results were statistically significant(P <0.05).The normalized wall shear stress(WSS)in the ruptured group was lower than that in the unruptured group,and the difference was statistically significant(P<0.001).There was no significant difference in oscillatory shear index(OSI)between the rupture group and the rupture group,and the results were not statistically significant.The low wall shear stress area(LSA)of the ruptured group was lower than that of the ruptured group,and the difference was statistically significant(P=0.003).Conclusion: Aspect ratio,Size ratio,inflow angle,low WSS and high LSA are related to the rupture of PCoA.Inflow angle can be used as an index to evaluate the rupture risk of PCoA aneurysms..