Correlation Analysis Of Neutrophil/Lymphocyte Ratio With GCS Score And With Rotterdam CT Score In Traumatic Brain Injury Patients

OBJECTIVE: To explore the correlation of NLR with GCS scores and Rotterdam CT scores in acute traumatic brain injury patients and the differences between NLR levels in different traumatic brain patients.Materials and Methods: A total of 173 patients with acute traumatic brain injury patients.injury admitted to the Department of Neurosurgery of the Second Affiliated Hospital of Fujian Medical University from January 1,2019 to December 31,2019 were retrospectively analyzed.Inclusion criteria: clear history of brain injury with a time window within 24 hours;exclusion criteria: 1.combined with severe multiple injuries;2.previous coronary heart disease,blood system disease,immune system disease;3.history of craniocerebral injury,brain Stroke history,other neurological diseases;4,acute and chronic infectious diseases,long-term use of hormones,immunosuppressive agents,etc.Patient data included gender,age,whether with hypertension,whether with diabetes,absolute neutrophil count,lymphocyte absolute value,patient consciousness at the time of admission,and skull CT examination within 24 hours of admission.The correlation of NLR with GCS scores and Rotterdam CT scores after admission were analyzed.The GCS scores and Rotterdam CT scores were divided into groups to study the differences in NLR levels between the groups.Statistical analysis was performed using SPSS 23.0 software.Measurement data conforming to the normal distribution by Shapiro–Wilk test are mean± standard deviation((?)± s).Comparison between multiple groups is analyzed by single factor analysis of variance,comparison between two groups uses Student’s t test,otherwise the median and four are used.The quantiles are expressed;the comparison between multiple groups uses the Kruskal-Wallis test,the pairwise comparison uses the Mann-Whitney U test;the correlation analysis uses Spearman’s Rho correlation analysis.Test level α = 0.05.Results: A total of 173 TBI patients were included to analyze the correlation between NLR levels and GCS scores.The results showed that there was a significant negative correlation between NLR levels and GCS scores in patients with acute brain injury(r =-0.863,P = 0.000 <0.05).The higher the NLR level,the lower the GCS score.Nine patients were excluded from the external hospital CT,and a total of 164 NLR levels were included in the correlation with the Rotterdam CT score.The results showed that the NLR levels in patients with acute brain injury had a strong positive correlation with the Rotterdam CT score.(r = 0.750,P = 0.000 <0.05),the higher the NLR level,the higher the CT score in Rotterdam.A total of 173 TBI patients were included and divided into three groups: mild,moderate and severe.The results showed that the GCS scores of the mild group were significantly different from the GCS scores of the moderate and severe groups,and the differences were statistically significant(P = 0.000).<0.05).There was a difference in NLR levels between the moderate GCS score group and the severe GCS score group,and the difference was statistically significant(P = 0.012 <0.05).A total of164 TBI patients were included and divided into mild and recombined.The results showed that the NLR levels of Rotterdam CT scores were different between the light and severe groups,and the difference was statistically significant(P = 0.000 <0.05).CONCLUSION: NLR levels and GCS scores are significantly negatively correlated when patients with acute traumatic brain injury are admitted to hospital,and have a positive correlation with Rotterdam CT scores.There were significant differences in NLR levels between TBI patients in different GCS score groups and different Rotterdam CT score groups.The higher the NLR,the more severe the patient’s condition.NLR may be used as an initial assessment of the severity of patients with acute traumatic brain injury at the time of admission to guide clinical treatment.