Analysis Of Thyroid Function Test Results Of A Physical Examination Population In Nanning,guangxi And Its Correlation With Physical Examination Indexes

Objective:To collect the data of a healthy population in Nanning,Guangxi,and to analyze and observe the detection rate of thyroid diseases,thyroid function and its relationship with various physical examination indexes.Methods:A total of 1059 people who had their thyroid function measured in the physical examination Department of the First Affiliated Hospital of Guangxi Medical University in 2019 were collected,among whom 263 people had their carotid intima-media thickness measured.Collect general data:sex,age,height,weight,body mass index,systolic blood pressure,diastolic blood pressure.Laboratory indexes:TSH,FT₃,FT₄,SUA,TC,TG,HDL-C,LDL-C,FPG,2h PG,Hb A1c.Imaging data:thyroid ultrasound and cervical vascular ultrasound.Grouping methods:1.Male and female groups according to their gender;2.Age groups:group A:<60 years old;Group B:60-69 years old;Group C:70-79 years old;Group D:≥80 years old;3.According to whether thyroid nodules were detected,they were divided into two groups:thyroid nodule group and non-thyroid nodule group.Results:1.The total detection rate of thyroid dysfunction was 8.12%,in which the detection rate of male was 6.80%and that of female was 14.69%.The detection rate of female was significantly higher than that of male（P<0.001）.The detection rates of clinical hyperthyroidism,subclinical hyperthyroidism,clinical hypothyroidism and subclinical hypothyroidism were 0.38%,0.85%,0.28%and 6.61%,respectively.2.There were significant differences in serum TSH and FT₃ levels among different age groups（P<0.05）.TSH increased with age,and FT₃ decreased with age.3.The detection rate of thyroid nodules was62.04%.The detection rate of male and female was 60.43%and 70.06%,respectively.The detection rate of female was higher than that of male（P=0.016）.The detection rate of thyroid nodule increased with age.The detection rate of women in each age group was higher than that of men.4.The detection rate of multiple nodules was higher than that of single nodules（58.14%vs41.86%）.With the increase of age,the proportion of multiple nodules increased.According to the detection rate,the order of different nodule properties is:mixed nodule（49.62%）,solid nodule（41.86%）,cystic nodule（8.52%）.Mixed nodules were predominant in males and solid nodules in females.5.The difference of TSH,FT₃ and FT₄ between the thyroid nodule group and the non-thyroid nodule group was not statistically significant.Older age and women are risk factors for thyroid nodules.6.The order of disease detection rate is dyslipidemia（74.03%）,overweight（46.55%）,hyperuricemia（26.91%）,hypertension（25.50%）,carotid atherosclerosis（19.07%）,diabetes（12.28%）and obesity（11.05%）.The detection rates of overweight,hyperuricemia and carotid atherosclerosis in males were significantly higher than those in females（P<0.05）.7.TSH was positively correlated with age,TC and LDL-C;FT₃ was negatively correlated with age;FT4 was negatively correlated with BMI.Conclusions:1.The detection rate of thyroid dysfunction in the physical examination population was 8.12%,of which the detection rate of men was 6.80%and that of women was 14.69%.The detection rate of women was higher than that of men.The detection rates of clinical hyperthyroidism,subclinical hyperthyroidism,clinical hypothyroidism and subclinical hypothyroidism were 0.38%,0.85%,0.28%and 6.61%,respectively.2.The detection rate of thyroid nodules in the physical examination population was 62.04%,of which the det ection rate of men was 60.43%and that of women was 70.06%.The detection rate of women was higher than that of men.3.Age and female are the risk factors of thyroid nodules,but thyroid function is not the risk factors of thyroid nodules.4.Abnormal thyroid function may affect blood lipid metabolism.Patients with abnormal thyroid function should have their blood lipid detected routinely.