Exploring The Reason And Significance Of Hypocalcaemia In Initial Phase For Severe Burn Patients

Objective:By analyzing the characteristics and potential risk factors related with hypocalcaemia in initial phase post-burn in severe burn patients,and then,tried to deduct the implication of hypocalcaemia in prognostic meaning,and provide basis for clinical application.Methods: A review of all medical records of acute severe burn patients from January 2010 to July 2015 for exploring the characteristics of burn by different age,gender,Causes of injury,total body surface area(TBSA),full-thickness burn area duration of injury to admission,and need mechanical ventilation or not.Results: A total of 142 severe burn patients were included.On admission 97.2% of patients were hypocalcaemia;36.6% of them could be found severe hypocalcaemia.The severe and non-severe hypocalcaemia group had significant difference in weight,total body surface area(TBSA),full-thickness burn area,duration of injury to admission and incidence of mechanical ventilation.Serum calcium level had no difference between two groups by different age,gender,TBSA,full-thickness area.Severe hypocalcaemia was correlative with flame burn,longer admission duration and mechanical ventilation.But severe hypocalcaemia,in initial phase,had no correlation with mortality.Conclusions: women less than 55 years old,woman with lager TBSA,men combined longer admission duration,flame burn combined longer admission duration,TBSA larger than 70% or full-thickness burn area larger than 30% are the main population of severe hypocalcaemia and serum calcium level significantly decreased.Hypocalcaemia in initial phase is a symbol of severity of injury could not a strong prognostic indicator of mortality for severe burn patients.