| The purpose of this study was to compare the healing responses, after two weeks of implantation, between porous-surfaced Ti-6Al-4V implants as controls and the same implant design with a submicron (0.3-0.5 {dollar}mu{dollar}m) layer of calcium phosphate (Ca-P) applied to the implant surface using the sol-gel technique. Seventeen rabbits were used in three experiments. In Experiment I, the proximal end of the right tibia in 10 rabbits received two transcortical implants, one Ca-P-coated and one control. In Experiment II, one of each implant type was placed into either the right or left tibia of 6 rabbits. Only 1 rabbit was used in Experiment III where one Ca-P-coated implant was installed in each of the left and right tibiae. Backscattered scanning electron microscopy and a Bioquant Image Analysis computer software package were used to analyze absolute bone contact length (ACL), contact length fraction (CLF), straight line endosteal bone growth (SLBG), absolute bone ingrowth area (ABIA), and bone ingrowth fraction (BIF). The results were submitted to Repeated Measures ANOVA. (Abstract shortened by UMI.)... |
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