| Objective:To study the effect of Badu Shengji San on wound healing caused by low-level simple anal fistula surgery.Methods:This study uses a randomized controlled study method.The study subjects were hospitalized from January 01,2019 to December 31,2019 in the Department of Anorectal Diseases,Dongzhimen Hospital,Beijing University of Traditional Chinese Medicine(TCM),with a clear diagnosis of low-level simple anal fistula,TCM syndrome differentiation based on downward flow of damp-heat,and anal fistulectomy was performed.60 patients meeting the test conditions were randomly divided into a experimental group and a control group of 30 cases each,in which the experimental group was dressed with BaDu ShengJi San gauze and the control group was dressed with FuFang HuangBaiYe gauze,once a day from the first day after the surgery.And record the total time of wound healing for each patient,record the wound area,longitudinal diameter,wound healing rate,wound secretion score,wound granulation growth score,wound edema score,wound pain score,and medication safety on the 1st,7th,14th,21st,and 28th days after surgery.All clinical observation data were statistically analyzed using SPSS21.0 software.Results:1.Both groups of patients completed the test without shedding or suspension.There was no significant difference in gender,age,and course of disease between the experimental group and the control group(P>0.05),and they were comparable;2.Overall efficacy:in the experimental group,26 cases(86.7%)were cured,4 cases(13.3%)were markedly effective,and the total effective rate was 100%;in the control group,19 cases(63.4%)were cured,10 cases(33.3%)were markedly effective,1 case(3.3%)was effective,and the total effective rate was 96.6%.There was no significant difference in overall efficacy between the experimental group and the control group(P>0.05);3.In terms of wound healing time:the longest time in the experimental group was 36 days and the shortest 20 days,with an average of 25.07 ± 3.83 days,and the longest time in the control group was 42 days and the shortest 23 days,with an average 28.50 ± 4.40 days.The time spent in the experimental group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05);4.In terms of wound area:there was no significant difference in the original wound area between the two groups(P>0.05),which is comparable.On the 7th day,the 14th day,the 21 st day,and the 28th day after the surgery,the wound area of the experimental group was smaller than that of the control group,and the differences were statistically significant(P<0.05);5.In terms of wound healing rate:the wound healing rate of the experimental group was significantly higher than that of the control group on the 7th day,the 14th day,the 21st day,and the 28th day after the surgery,and the difference was statistically significant(P<0.05);6.In terms of longitudinal diameter of the wound:There was no significant difference in the longitudinal diameter of the wound on the first day after surgery between the two groups(P>0.05),which is comparable.On the 7th day,the 14th day,the 21st day,and the 28 th day after the surgery,the longitudinal diameter of the wounds in the experimental group were smaller than those in the control group,and the differences were statistically significant(P<0.05);7.In terms of wound secretion score:There was no difference in wound secretion score between the two groups on the first day after surgery(P>0.05);on the 7th day after surgery,the wound secretion score in the experimental group was higher than the control group,and the difference was statistically significant(P<0.05);the scores of the experimental group were lower than those of the control group on the 14th day,the 21st day,and the 28th day after the surgery,and the difference was statistically significant(P<0.05);8.In terms of wound granulation tissue growth scores:the wound granulation tissue growth scores of the experimental group on the 7th day,the 14th day,and the 21st day after the surgery were lower than those of the control group,and the difference was statistically significant(P<0.05);On the 28th day,the granulation tissue growth score of the experimental group was lower than that of the control group too,but the difference was not statistically significant(P>0.05);9.In terms of wound edema scores:the scores of wound edema in the experimental group were lower than those in the control group on the 7th day,the 14th day,and the 21 st day after the surgery,and the difference was statistically significant(P<0.05);On the 28th day,the wound edema score in the experimental group was lower than that in the control group too,but the difference was not statistically significant(P>0.05);10.In terms of wound pain scores:there was no significant difference in wound pain scores between the two groups on the first day after surgery(P>0.05),and they were comparable.On the 7th day and the 14th day after the operation,the wound pain scores in the experimental group were lower than those in the control group,and the difference was statistically significant(P<0.05).On the 21st day and the 28th day after surgery,the wound pain scores in the experimental group were also lower than that in the control group,but the difference was not statistically significant(P>0.05);11.No adverse reactions were seen in all cases.Conclusion:The use of Badu Shengji San for dressing changes in low-level simple anal fistula can significantly shorten the wound healing time,promote the reduction of wound area,shorten the longitudinal diameter,and improve the wound healing rate.In the early stage of wound healing,pus can be removed and the necrotic tissue can be promoted.In the middle and late stages of healing,it can gather sore muscles,promote the growth of granulation tissue,accelerate healing,and have the efect of reducing wound edema and wound pain,and it is safe and effective in clinical application. |
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