| Objective:This study observed by the medical infrared thermal imaging technology of ITP children and healthy children of infrared thermal imaging characteristic,to study the difference between ITP children and healthy children’s infrared thermogram.This study attempts to combine the non-invasive and non-radiation infrared thermal imaging technology with the pathogenesis of ITP children and the TCM theory,in order to provide an objective and quantitative visualization index for the observation and evaluation of the clinical efficacy,pathogenesis of TCM,syndrome differentiation and classification of children with ITP.Methods:According to the inclusion criteria and exclusion criteria,85 patients were included in this study,in which children with ITP 50 cases,35 cases of healthy children,acquisition of two groups of infrared thermal imaging figure,the general situation and the clinical data of children with ITP group information(including medical history,four diagnostic information of TCM,routine blood test),Setting the average temperature of the area to be studied as T1,the average temperature of the trunk area as T2,T2=(the average temperature of the front of the trunk+the average temperature of the back of the trunk)/2,and the relative thermal difference of the area to be studied as the relative thermal calorific value data(△t)=T1-T2.The difference of the relative thermal calorific value data(△t)between the two groups was recorded in the areas of eyes,mouth,forehead,nose,left cheek,right cheek,chin,the areas of the five organs:liver,heart,spleen,lung,kidney,Ren meridian area and Du meridian area.and the non-uniformity of trunk,tri-jiao and back were recorded In this study,we will compare the difference of △T and the non-uniformity between different areas of ITP group and healthy group,and further explore the correalation between the different areas’ the relative thermal calorific value data,the non-uniformity of different areas in ITP group and other clinical information.Results:1.The infrared thermal imaging features of children with ITP were as follows:the forehead area and the eye area showed diffuse red areas with abnormal high temperature,and the range of physiological thermal areas was larger than that of the healthy group;The nose area is red and warm;Both lateral cheeks show yellow-green abnormal temperature zone;Low temperature zone and discontinuous thermal structure were found in the back area.The trunk’s heat state distribution is not uniform,the performance is granophyric shape,and there is a significant difference with the healthy children’s infrared thermal imaging2.ITP group and healthy group were compared with the five internal organs areas of the relative thermal calorific value data,the difference was not statistically significant(P>0.05).In the ITP group,liver area、heart area、spleen area、lung area’s the relative thermal calorific value data were higher than health group’s.renal area’s the relative thermal calorific value data of Healthy group was higher than ITP group;s.The area of spleen was the highest temperature of five internal organs in the ITP group3.ITP group and healthy group were compared with the various parts of the face of the relative thermal calorific value data.The left cheek area,right cheek area and chin area of the relative thermal calorific value data in ITP group were higher than healthy group(P<0.05).There was no significant difference between the two groups in eye area,mouth area,forehead area and nose area of the relative thermal calorific value data(P>0.05),but the temperature of eye area,mouth area,forehead area and nose area’s the relative thermal calorific value data in ITP group were higher than healthy group.4.There was no significant difference between ITP group and healthy group in Ren meridian and Du meridian area of the relative thermal calorific value data(P>0.05),However,the temperature showed that:the order of Du meridian area’s the relative thermal calorific value data:ITP group<healthy group,the order of Ren meridian area of the relative thermal calorific value data:ITP group>healthy group.In the ITP group,Ren meridian area of the relative thermal calorific value data was higher than Du meridian area’s.In the healthy group,Du meridian area’s the relative thermal calorific value data was higher than Ren meridian area’ s5.The back’s non uniformity of ITP group was higher than that of healthy group,of which the difference between two groups was statistically significant(P<0.05).The difference in tri-jiao’s and back’s non uniformity between the two groups was not statistically significant(P>0.05).The non-uniformity of trunk and tri-jiao in ITP group was greater than that in healthy group6.There was no significant difference in the facial areas,he five internal organs areas,Ren meridian and Du meridian areas of the relative thermal calorific value data among the different clinical types(P>0.05).In the new diagnosis group,the facial areas,the five internal organs areas of the relative thermal calorific value data>chronic group>persistent group;Chin area of the relative thermal calorific value data:chronic group>persistent group>new diagnosis group.Ren meridian area of the relative thermal calorific value data:chronic group>persistent group>new diagnosis group;Du meridian area of the relative thermal calorific value data:persistent group>new diagnosis group>chronic group;new diagnosis group:Du meridian area of the relative thermal calorific value data>Ren meridian area’ s;persistent group:Du meridian area of the relative thermal calorific value data>Ren meridian area’ s;chronic group:Ren meridian area of the relative thermal calorific value data>Du meridian area’ s.The difference of trunk’ s non uniformity among different clinical types showed that the new ITP diagnosis group had trunk heterogeneity>persistent group>chronic group(P<0.05).Further comparison between the two groups showed that the difference was statistically significant(P<0.05).There was no significant difference between the clinical types(P>0.05).7.There was no significant difference in the facial areas,the five internal organs areas,Ren meridian and Du meridian areas of the relative thermal calorific value data between the group that had used hormone in the last month and the group that had not used hormone in the last month(P>0.05).The difference of the relative thermal calorific value data in facial parts.the five internal organs areas,Ren meridian and Du meridian areas between the two groups was:the group without hormone in the past month>the group with hormone in the past month.The difference in the tri-jiao’s non uniformity was statistically significant between the groups that had used hormone in the last month and those that had not used hormone in the last month,and the group without hormone in the past month>the group with hormone in the past month.8.There was no significant difference in the facial areas,the five internal organs areas,Ren meridian and Du meridian areas of the relative thermal calorific value data between the anaemic group and the non anaemic group(P>0.05).However,the relative thermal calorific value data of the facial areas(except left cheek and right cheek areas),the five internal organs areas.Ren meridian areas between the two groups was:anemia group<non anemia group.In the anemia group,left cheek area,right cheek area,and Du meridian area’s the relative thermal calorific value data>the non anemia group’s.There was no significant difference in the non-uniformity of trunk,tri-jiao and back between the anemia group and the non anemia group(P>0.05),but the results showed that the non anemia group was higher than the anemia group9.The results showed that there was no significant difference in the facial areas,the five internal organs areas,Ren meridian and Du meridian areas of the relative thermal calorific value data among different platelet count groups(P>0.05).The relative thermal calorific value data of each region in different platelet groups was sequenced from high to low.It was found that the relative thermal calorific value data sequence of nose in PLT(0～29)×109/L group,PLT(30～49)×109/L group was higher than that in PLT(≥100)×109/L group、PLT(50～99)×109/L group,suggesting that there may be a positive correlation between the platelet count and the temperature of the nose.The lung area’s the relative thermal calorific value data of PLT(0～29)×109/L group and PLT(30～49)×109/L group was higher than that of PLT(50～99)×109/L group and PLT(≥100)×109/L group.PLT(30～49)×109/L group and PLT(≥100)×109/L group:Ren meridian area of the relative thermal calorific value data>Du meridian area’s;PLT(0～29)×109/Lgroup and PLT(50～99)×109/L group:Du meridian area of the relative thermal calorific value data>Ren meridian.There was no significant difference in the non-uniformity of trunk,tri-jiao and back among different platelet count groups(P>0.05).But with the increase of platelet count,the non-uniformity of ITP children decreased.10.There was no significant difference in the facial areas,the five internal organs areas,Ren meridian and Du meridian areas of the relative thermal calorific value data in different TCM syndromes(P>0.05).The relative thermal calorific value data sequence in the facial areas(except frontal area)among different TCM syndromes was:the syndrome of bleeding due to blood heat>the syndrome of yin deficiency and blood heat>the syndrome of qi failing to control blood.There was statistical significance in the forehead area of the relative thermal calorific value data among different TCM syndromes(P<0.05),The forehead area of the relative thermal calorific value data:the syndrome of yin deficiency and blood heat>the syndrome of qi failing to control blood.The relative thermal calorific value data of the five internal organs areas(except spleen area)among different TCM syndromes:the syndrome of bleeding due to blood heat>the syndrome of yin deficiency and blood heat>the syndrome of qi failing to control blood.The relative thermal calorific value data of spleen area temperature was:the syndrome of yin deficiency and blood heat>the syndrome of bleeding due to blood heat>the syndrome of qi failing to control blood.The Ren meridian and Du meridian areas of the relative thermal calorific value data in different TCM syndromes:the syndrome of bleeding due to blood heat:Du meridian area of the relative thermal calorific value data>Ren meridian area’s;Yin deficiency and blood heat syndrome:Ren meridian area of the relative thermal calorific value data>Du meridian area’s;the syndrome of qi failing to control blood:Du meridian area of the relative thermal calorific value data>Ren meridian area’s.There was no significant difference in the non-uniformity of ITP among different TCM syndrome types(P>0.05),But the order of the non-uniformity among different TCM syndromes was:the syndrome of bleeding due to blood heat>the syndrome of yin deficiency and blood heat>the syndrome of qi failing to control blood11.There was no significant difference in the non-uniformity of trunk,tri-jiao and back between the two groups(P>0.05)Conclusion:1.The temperature of left cheek,right cheek and chin in ITP group was higher than that in healthy group,and there were differences in forehead temperature among different TCM syndrome differentiation types2.The non-uniformity of ITP group was higher than that of healthy group,especially in the back.In addition,there are differences in trunk heterogeneity among different clinical types,and there is a correlation between the non-uniformity of tri-jiao and whether the hormone has been used in the past month.Different platelet counts and different TCM syndromes may also influence the non-uniformity of children with ITP.3.The infrared thermal imaging features of children with ITP were as follows:the forehead area and the eye area showed diffuse red areas with abnormal high temperature,and the range of physiological thermal areas was larger than that of the healthy group;The nose area is red and warm;Both lateral cheeks show yellow-green abnormal temperature zone;Low temperature zone and discontinuous thermal structure were found in the back area.The trunk’ s heat state distribution is not uniform,the performance is granophyric shape,and there is a significant difference with the healthy children’s infrared thermal imaging,and there is a significant difference with the healthy children’s infrared thermal imaging.It may provide objective and quantitative visualization indexes for the clinical diagnosis and treatment of children with ITP and the dynamic monitoring of the disease in the future. |
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