| Impaired glucose tolerance in pre-diabetes is a common metabolic disease.It is the intermediate transition period between normal glucose tolerance and type 2 diabetes.It can maintain the status quo or return to normal.It can also develop into type 2diabetes.One of the important comprehensive treatments for the treatment of diabetes plays an irreplaceable role.Among them,Health Qigong Baduanjin is gradually applied to people with impaired glucose tolerance as a safe and effective exercise method.However,the research on the assessment of the effect of Baduanjin exercise on people with impaired glucose tolerance is currently focused on endocrine and musculology.The energy metabolism mechanism is closely related to the pathogenesis of impaired glucose tolerance.Regarding exercise intervention,especially the effect of traditional sports intervention on energy metabolism in people with impaired glucose tolerance,it is still rare and there is no unified conclusion.Purpose:To observe the effect of Health Qigong Baduanjin exercise on energy metabolism in people with impaired glucose tolerance in pre-diabetes,and to explore the related energy metabolism mechanism of Health Qigong Baduanjin exercise to improve people with impaired glucose tolerance under quiet and quantitative load conditions.The research conclusion can provide a certain theoretical basis for enriching the effects of Health Qigong Baduanjin exercise intervention on pre-diabetes population,and provide a practical basis for the role of traditional sports in the intervention of pre-diabetes.Method:35 people with pre-diabetes impaired glucose tolerance who met the inclusion criteria were selected.However,due to the low attendance rate of the subjects during the intervention and the loss of household chores,a total of 3 persons were lost,a total of32 people participated in the experiment before and after the intervention,including21 women and 11 males,aged 65±4.5 years old,randomly divided into two groups,the experimental group(n=17)and the control group(n=15).The experimental group performed Baduanjin exercise and the control group performed resistance exercise.The group intensively exercised 3 times a week for 40 minutes each time for a total of 12 weeks of intervention.Inbody770(Korea)is used to measure body composition(weight,BMI,body fat,body fat percentage,and lean body mass);tape measure is used(waist and hip circumference);Hospital tests for blood biochemical indicators(fasting blood glucose,2 hour postprandial blood glucose,glycated hemoglobin,triglycerides,cholesterol,low density lipoprotein,high density lipoprotein,insulin,insulin 120min,HOMA-IR、HOMA-IS、HOMA-β);using hand-held electronic muscle strength The measuring instrument FET3(USA)measures the muscle strength of both lower limbs(bilateral quadriceps,bilateral hamstrings);the cardiopulmonary function test system COSMED cardiopulmonary function instrument(Germany)measures the energy metabolism at rest(heart rate,respiratory quotient,sugar oxidation amount,fat oxidation amount,resting energy consumption,relative resting energy consumption);using exercise cardiopulmonary function test system COSMED cardiopulmonary function instrument(Germany)and Cosmos Pulsar4.0 activity treadmill(Germany)to measure energy metabolism during quantitative load(Heart rate,oxygen uptake,relative oxygen uptake,respiratory quotient,sugar oxidation amount,fat oxidation amount,energy consumption,relative energy consumption).Indicators were measured before the intervention and after 12weeks of intervention.Statistical methods the measurement data conforms to the normal distribution using the t test,and does not conform to the normal distribution using the rank sum test to calculate the statistic Z,the significance levelα=0.05.Result:1.Changes in blood glucose and lipid between the two groups of subjects before and after the intervention:after 12 weeks of intervention,within-group comparison:2hours postprandial blood glucose(mmol/L),glycated hemoglobin(%),glycerin Triester(mmol/L),total cholesterol(mmol/L),low-density lipoprotein(mmol/L),insulin(uIU/mL),and HOMA-IR were lower than before intervention(P<0.05).The subjects’fasting blood glucose(mmol/L)and insulin for 120 minutes(uIU/mL)were lower than before the intervention(P<0.05),the HOMA-IS and HOMA-βwere higher than before the intervention(P<0.05),while the experimental group The four indicators of the subjects were not significantly different from that before the intervention(P>0.05),and the high-density lipoprotein(mmol/L)of the two groups of subjects was not significantly different from that before the intervention(P>0.05).Comparison between groups:experimental group subjects’2-hour postprandial blood glucose lowered after intervention(8.31±0.59 vs 8.88±0.97)was better than the control group(P<0.05),the control group subjects’glycated hemoglobin decreased after intervention[5.8(5.59,6.01)]vs 6.09(5.67,6.19)],and the increase in HOMA-β(115.12±31.81 vs 97.04±5.88)were superior to the experimental group(P<0.05).2.Changes in body composition and lower extremity muscle strength of the two groups of subjects before and after the intervention:after 12 weeks of intervention,comparison within the group:body weight(kg),BMI(kg/m~2),body fat(kg),body fat percentage(%),waist-to-hip ratio of the experimental group and the control group were lower than before intervention(P<0.05),fat-free body weight(kg),muscle strength of both quadriceps muscles(kg)were higher than before intervention(P<0.05);the muscle strength(kg)of bilateral hamstrings in the control group was higher than before the intervention(P<0.05),but there was no significant difference in this group of indicators in the experimental group than before the intervention(P>0.05).Comparison between groups:body fat(19.63±1.43 vs 22.11±1.96),body fat percentage(32.35±2.12 vs 35.13±3.72),waist-to-hip ratio(0.84±0.05 vs 0.88±0.06)All three indicators better than the control group(P<0.05).The muscle strength of the quadriceps muscles of the control group after intervention(left:36.87±6.08 vs32.44±5.91,right:39.71±6.36 vs 34.93±5.48),the muscle strength of the bilateral hamstring muscles(left:22.17±3.80 vs 17.54±2.93,right:23.54±3.87 vs19.05±2.97)The increase was better than the experimental group(P<0.05).3.Changes in quiet energy metabolism between the two groups of subjects before and after the intervention:after 12 weeks of intervention,the comparison within the group:the heart rate(beats/min)of the experimental group and the control group was lower than before the intervention(P<0.05),respiratory quotient,The amount of sugar oxidation(g/min)and the relative resting energy expenditure(cal/min/kg)were higher than before the intervention(P<0.05),and the amount of fat oxidation(g/min)of the two groups of subjects was no significant change than before(P>0.05),and the resting energy expenditure(cal/min)of the experimental group subjects was not significantly changed before intervention(P>0.05),The resting energy expenditure of the control subjects was higher than before the intervention(P<0.05).Comparison between groups:The increase in resting energy expenditure of the control group after intervention[1297.33(1109.92,1736.25)vs 1104.01(984.53,1146.74)]was better than experimental group(P<0.05).4.Changes in energy metabolism during quantitative load between the two groups of subjects before and after the intervention:After 12 weeks of intervention,the heart rate(beats/min),oxygen uptake(mL/min),and fat oxidation amount(g/min)of the experimental and control subjects were lower than before intervention(P<0.05),respiratory quotient and sugar oxidation amount(g/min)were higher than before intervention(P<0.05),the relative oxygen uptake of the experimental group and the control group of subjects(mL/min/kg),energy consumption(cal/min),and relative energy consumption(cal/min/kg)were not significantly different than before intervention(P>0.05).Comparison between groups:The increase in respiratory quotient[0.89(0.87,0.91)vs 0.85(0.84,0.87)]of the experimental group after intervention was better than control group(P<0.05).Conclusion:1.The 12-week Health Qigong Baduanjin exercise can improve the glucose and lipid metabolism level and insulin secretion level of people with impaired glucose tolerance in prediabetes.2.The 12-week Health Qigong Baduanjin exercise can increase the amount of sugar oxidation in people with impaired glucose tolerance during pre-diabetes during quiet and quantitative load,promote the balance of substrate metabolism,and improve energy metabolism.Related to improved energy metabolism.3.The 12-week Health Qigong Baduanjin exercise can change the physical function of people with impaired glucose tolerance in prediabetes,It is suggested that the intervention effect of Health Qigong Baduanjin exercise is equivalent to resistance exercise,which can be used as a safe and effective exercise method for people with impaired glucose tolerance in pre-diabetes,and it is worth promoting. |
PDF Full Text Request