The Study Of Multi-b Value DWI In Predicting The Texture Of Pituitary Tumors Before Operation

Objective: To explore the application value of Multiple b-Value DWI and ADC in predicting the the consistency of pituitary adenomasMaterials and Methods: Fifty-seven patients confirmed with pituitary adenoma pathologically were included in the research.All patients were underwent examination,which included 3.0 T MRI multiple b-value(b = 0,1000,2000 s/mm2)DWI scan and endocrine hormone.Volumes of interest(VOIs)were drawn in the pituitary adenomas on ADC maps generated with two b-values(b =1000,2000s/mm2).Consistency of pituitary adenomas was evaluated at surgery and classified as soft group or hard group.The relationship between the consistency of tumor with mean ADC values,patients’ age,gender,hormone classification and collagen contents in tumors were analyzed under two b values.Results: Statistical analysis revealed no obvious correlation in b1000(p<0.05)but a significant correlation in b2000(p > 0.05)between the tumor consistency and mean ADC values.No other obvious correlations were found between tumor consistency with the patients’ age,gender or hormone classification in neither b1000 nor b2000,but collagen contents in tumors had a significant correlation with the tumor consistency in both b1000 and b2000.Conclusion: Tumor consistency of pituitary adenomas has close relationship with mean ADC values and collagen contents in tumors but has no relationship with the patient’s gender,age or hormone classification.DW MR images with ADC values can be used to predict the the consistency of Pituitary adenomas,which provide important imaging basis for the choice of surgical approach.