| Chronic cough is the most common condition in respiratory diseases.Related studies have shown that the global prevalence of chronic cough is 9.6%.In the United States,20%to 30%of specialist outpatients are seen for chronic cough,and their prevalence is on the rise.Chronic cough with cough as the main or only symptom,the clinical symptoms are lack of specificity,and the cause is complicated,the diagnosis is unknown,and the simple treatment of western medicine is not effective very well,which has become one of the research hotspots in the respiratory world of Chinese and Western medicine.The theory of viscera is an important part of TCM Viscera doctrine,and it is the interpretation of the relationship between viscera physiology,pathology and mutual influence.In recent years,the application of the theory of viscera in lung diseases has been increasing.In the pathogenesis of lung diseases,lung and liver,spleen,kidney,stomach and other multi-viscera related pathogenesis can be seen.The lung and spleen-related pathogenesis is the most common.Many doctors have discussed the theory and clinical application of lung and spleen;among them,the lung and spleen-related pathogenesis of chronic cough has also attracted increasing attention and deserves further investigation.ObjectiveThrough the observation of previous medical history,pathological characteristics,symptoms and signs and characteristics of syndromes and pathogenesis of chronic cough,the characteristics of chronic cough and spleen-related pathogenesis were summarized,and the clinical system of chronic cough was further improved.And this research provided a basis for improving the clinical differentiation of chronic coughMethodsUsing retrospective research methods,outpatients who met the diagnostic criteria for chronic cough from January 2009 to February 2018 were selected as subjects,and the general information of patients,predisposing factors and other medical diagnostic information were collected,and EpiData software was used to establish a chronic cough database.The database is converted into a specification database supported by SPSS statistical software,and statistical analysis is performed on the data by using SPSS20.0 statistical software.Results1.A total of 724 cases of chronic cough were collected in this study,including 499 cases of chronic cough with lung and spleen-related pathogenesis,accounting for 68.92%.2.There are more female patients with chronic cough in the pathogenesis of lung and spleen,accounting for 70.54%.3.The median age of patients with chronic cough with lung and spleen-related pathogenesis is 53(41,62)years old,and their age group is mostly in the middle-aged group.4.The median duration of patients with chronic cough with lung and spleen-related pathogenesis is 2 years(6 months,7 years).5.In the past medical history,there are 28 cases of digestive diseases,including reflux esophagitis,peptic ulcer,superficial gastritis,chronic colitis,other past diseases can also be seen allergic rhinitis,metabolic diseases(Diabetes,hyperlipidemia,gouty arthritis,hypertension,etc.can be seen in this study).6.The cause of chronic cough with lung and spleen-related pathogenesis(occurrence frequency is greater than 10%)in order:odor,inhaling cold air catarrh,talking and laughing;dietary factors commonly include eating spicy,salty,cold,sweet,greasy food.And its onset season is most in winter.7.Symptoms and signs of patients with chronic cough in the pathogenesis of lung and spleen(occurrence frequency greater than 10%)in order:throat itching,dry mouth,less phlegm,cough,white phlegm,cold back,want to drink water,mouth bitterness,innocent,sticky mouth,drink not quenching thirst,more phlegm,acid reflux,sticky stool,cold stomach,phlegm thick,dry throat,do not want to drink water,cough loud,palm heat,no sweat,loose stools,sweat more,chest tightness,stubborn sputum,fear of cold,dry stool;tongue images like red or reddish,yellow moss,white moss,greasy moss,thick moss is common;slippery,string and fine pulse is common.The common symptoms of the group of patients in different age group are different.8.Pathogenesis characteristics of chronic cough with lung and spleen-related characteristics can be seen:intermingled deficiency and excess,cold and heat coexistence,the main syndromes can be seen:damp heat lung syndrome,lung spleen yang deficiency syndrome,phlegm dampness obstructing the lung syndrome.Other common pathogenesis can be seen;wind evil lung syndrome,lung yang deficiency,cold drink lung syndrome,etc.Different age groups of patients with chronic cough in the pathogenesis of lung and spleen have different characteristics of the syndrome distribution.Conclusion1.The lung and spleen-related pathogenesis is one of the common pathogenesis features of chronic cough.2.The clinical characteristics of patients with chronic cough in the pathogenesis of lung and spleen can be seen:①the patient’s gender is mostly female;②patients are older and have a longer course of disease;③patients with cough are often associated with dietary factors,cold,anti-Acid burning heart and other factors,which closely related to spleen and stomach function damage;④patients with symptoms can be seen:pulmonary symptoms are the same as common symptoms of chronic cough,spleen symptoms are complex and diverse,common spleen symptoms are dry mouth,want to drink water,mouth bitterness,sticky mouth,drinking and not quenching thirst,acid reflux,sticky stool,cold stomach,do not want to drink water,loose stools,dry stools,etc.3.Pathogenesis characteristics of chronic cough with lung and spleen-related characteristics can be seen:intermingled deficiency and excess,cold and heat coexistence,the main syndromes can be seen:damp heat lung syndrome,lung spleen yang deficiency syndrome,phlegm dampness obstructing the lung syndrome.Other common pathogenesis can be seen:wind evil lung syndrome,lung yang deficiency,cold drink lung syndrome,etc. |