Analysis Of Related Factors Of No Reflow-coronary Slow Flow In STEMI Patients After PCI

Objective:To explore the risk factors of no reflow-coronary slow flow(NR/CSF)in patients with acute ST segment elevation myocardial infarction(STEMI)after PCI,and to propose a new method for predicting the classification of coronary lesions in NR/CSF-a self-defined method for the determination of thrombus overload in coronary angiography.Methods:185 patients with STEMI and PCI were selected from the Department of Cardiology of our hospital,including 37 patients with NR/CSF and 148 patients with normal blood flow.To collect and compare the clinical data and coronary angiography data of these two kinds of patients.Results:The hospital mortality rate of patients without reflow and slow blood flow group was 4 times higher than that of normal reflow group.The results of single factor analysis showed that the elderly,diabetes mellitus,preoperative Killip grade > 1,long time of ischemia,high thrombus load and coronary angiography thrombus overload in the non reflow slow flow group were significantly higher than those in the normal flow group.The results of multivariate logistic regression analysis showed that age was not an independent risk factor.Among the clinical factors,diabetes mellitus,Killip grade > 1,long time of ischemia,high thrombus load or coronary angiography thrombus overload were independent risk factors of no reflow slow blood flow,and the or value of coronaryangiography thrombus overload was higher than that of high thrombus load.Conclusion:Patients with STEMI who had no reflow slow blood flow after PCI had poor survival rate;patients with diabetes mellitus,Killip grade > 1,long time of ischemia,high thrombus load and coronary angiography thrombus overload had high incidence of no reflow slow blood flow.In addition,the self-defined method for the determination of thrombus overload in coronary angiography has a good predictive value for no reflow slow flow.