Application Value Of EBUS And Virtual Navigation Technology Combined With Rapid On-Site Detection In Peripheral Lung Lesions

Objective:To investigate the value of endobronchial ultrasound(EBUS)and virtual bronchoscopic navigation(VBN)combined with rapid on-site evaluation(ROSE)in lung peripheral biopsy.Methods:100 patients in zhangzhou fujian hospital from November 2018 to March 2018 with peripheral pulmonary lesions were randomly divided into ROSE biopsy group(test group)and non-ROSE group(control group)based on virtual navigation,all combined with EBUS.The positive rate of brushing,the positive rate of biopsy,the positive rate of brushing plus biopsy,the complications,the time from the first biopsy to the time of diagnosis,the cost during the time from the first biopsy to the diagnosis and treatment,the location of the biopsy,and the size of the lesion were counted.The positive rate of brushing,the positive rate of biopsy,the complications,the time from the first biopsy to the diagnosis,the cost during the time from the first biopsy to the diagnosis and treatment,the positive rate of the same part of the two groups,the positive rate between the two groups that the diameter of which were ≤3cm and >3cm,all the indexes were analyzed.Results:There were 50 patients in the experimental group,the positive rate of brushing was 68%(34/50),the positive rate of biopsy was 84%(42/50),the positive rate of brushing plus biopsy was 84%(42/50),and the incidence of mass bleeding was 0.0%(0/50),the incidence of pneumothorax was 0%(0/50),the average time from the first biopsy to the diagnosis was 3.84±4.28 days,the cost was 4093.15±4494.67 yuan,and the positive rate of the posterior segment of the upper tip was 70.%(7/10),the positive rate of the anterior segment of the upper lobe was 100%(9/9),the positive rate of the basal segment of the lower lobe was 90.9(10/11),and the positive rate of the lower lobe was 62.5%(5/8),the positive rate of diagnosis in the middle lobe or tongue segment was 91.6%(11/12),the diagnostic positive rate of the ones that diameter ≤3cm was 75%(18/24),and >3cm was 96.1%(25/26).Ther were 50 patients in the control group,the positive rate of brushing was 44%(22/50),the positive rate of biopsy was 74%(37/50),the positive rate of brushing plus biopsy was 74%(37/50),and the incidence of mass bleeding was 0.%(0/50),the incidence of pneumothorax was 0%(0/50),the average time from the first biopsy to the time of diagnosis was 6.46±3.66 days,the cost was 6420.28±4541.33 yuan,and the positive rate of the posterior segment of the upper tip was 63.6%.(7/11),the positive rate of the anterior segment of the upper lobe was 90%(9/10),the positive rate of the basal segment of the lower lobe was 77.7%(7/9),and the positive rate of the lower lobe was 66.7%(6/9),the positive rate of diagnosis in the middle lobe or tongue segment was 81.8%(9/11),the diagnostic positive rate of of the ones that diameter ≤3cm was 56.5%(18/24),and >3cm was 88.9%(24/27).Conclusion:Combined ROSE can improve the diagnostic rate of VBN-EBUS in peripheral lung lesions and shorten the time of diagnosis and reduce the medical expenses during the examination to the diagnosis.There was no statistically significant difference in the positive rate of diagnosis between different lesions except for the application of ROSE in the anterior segment of the upper lobe.Except the improvement of the positive rate of brushing more than 3cm,there was no statistical difference in the positive rate of the combined ROSE for the statistical.