Study On The Distribution Of Diseases During Pregnancy And The Influencing Factors Of Pregnancy Outcome In Chongqing

Objective This study describes the distribution of pregnant women’s diseases during pregnancy in Chongqing by analyzing the retrieval data of YIDUCLOUD database,explores the relevant influencing factors of pregnancy outcome,and timely understands the situation of pregnant women from pregnancy to delivery,so as to provide scientific basis for clinical attention and reduce the occurrence of adverse pregnancy outcomes.Methods The data of this study was from the medical records of pregnant women from February 2012 to March 2018 in 3 hospitals in Chongqing retrieved by the medical data intelligent platform of YIDUCLOUD.Excel was used to check and sort out the general data of pregnant women,previous pregnancy and childbirth situation,prenatal examination record and pregnancy outcomes,etc.SPSS 24.0 statistical software was used for statistical analysis.The measurement data is expressed in(?±s),and the counting data was expressed in the rate(%).The distribution of diseases in different types of pregnant women was compared byχ~2 test or Fisher’s exact probability test,and the influencing factors of adverse pregnancy outcome were analyzed by multi factor two classification logistic regression.Results(1)The top 3 diseases of 5038 pregnant women were umbilical cord around neck(20.40%),premature rupture of membranes(20.01%),scar uterus/GDM(16.47%).The incidences of GDM,syphilis,macrosomia,placenta previa,polyhydramnios and scar uterus in elderly pregnant women were significantly higher than that in normal pregnant women(P<0.05).The top three diseases of pregnant and lying-in women without regular prenatal examination are premature rupture of membranes(22.18%),umbilical cord around neck(19.81%),scar uterus(19.61%).The incidence rate of hypertensive disorder complicating pregnancy,intrahepatic cholestasis of pregnancy,gestational diabetes mellitus,thrombocytopenia,fetal growth restriction,macrosomia,fetal distress,placenta previa,oligohydramnios and other diseases in the distribution of cesarean section diseases was significantly higher than that of vaginal delivery pregnant women(P<0.05).(2)Multivariate logistic regression analysis showed that the factors that increased the risk of hypertensive disorders complicating pregnancy(OR>1)were overweight/obesity before pregnancy,excessive weight gain during pregnancy,GDM and number of pregnancies≥5 times;The factor that reduced the risk was delivery≥1 time.(3)The factors that increased the risk of GDM were age≥25 years old,overweight/obesity before pregnancy,low weight gain during pregnancy,hypertensive disorders complicating pregnancy,previous cesarean section history and number of pregnancies≥2 times;The factors that reduced the risk were emaciation before pregnancy,excessive weight gain during pregnancy and delivery≥1time.(4)The factors that increased the risk of anemia in pregnancy were emaciation before pregnancy and no folic acid supplement;The factors that reduced the risk were aged 25~34 years and obesity before pregnancy.(5)The factor that increased the risk of hypothyroidism during pregnancy was no folic acid supplement;The factor that reduced the risk was delivery≥1time.(6)The factors that increased the risk of premature rupture of membranes were GDM and prenatal examination<7 times;The factors that reduced the risk were hypertensive disorders complicating pregnancy,delivery≥1 time and previous cesarean section.(7)The factors that increased the risk of preterm delivery were low weight gain during pregnancy,hypertensive disorders complicating pregnancy,prenatal examination<7 times,previous cesarean section history,pregnancy times≥5 times,premature rupture of membranes and placenta previa.(8)The factors that increased the risk of low birth weight infants were emaciation before pregnancy,low weight gain during pregnancy,hypertensive disorders complicating pregnancy,hepatitis B,prenatal examination<7 times and gestational age<37 weeks;The factor that reduced the risk was excessive weight gain during pregnancy.(9)The factors that increased the risk of macrosomia were excessive pregnancy weight gain,GDM,hepatitis B and polyhydramnios;The factors that reduced the risk were low weight gain during pregnancy and gestational age<37 weeks.Conclusions There are more than 20 kinds of diseases that often occur during pregnancy in this study.Different types of pregnant women have different distribution of diseases during pregnancy.Among them,the number of diseases that seriously threaten the health of mothers and infants among the elderly and pregnant women who do not have regular prenatal examination has increased significantly.Different influencing factors lead to different pregnancy outcomes,including hypertensive disorder complicating pregnancy,gestational diabetes mellitus,premature delivery and low birth weight infants have many influencing factors,which are more closely related to BMI before pregnancy,weight gain during pregnancy and the number of prenatal examinations.Pregnant women should strengthen diet intervention and weight management from the time of preparation of pregnancy,make special records of risk factors during pregnancy,regularly monitor possible complications of high-risk pregnancy,insist on regular prenatal examination and pregnancy care,improve pregnant women’s awareness of health protection,and thus improve maternal and infant outcomes.