Study On The Effect Of Body Position And Exercise On Young’s Modulus Of Liver By RT-SWE

Objective: To evaluate whether the Young’s Modulus of the liver in healthy volunteers is affected by receptor position and exercise,and provide a basis for further standardizing the application of RT-SWE.Methods: The Young’s modulus of the liver in the supine position and the left lateral position was measured in 79 healthy volunteers under quiet conditions,as well as the hypothesis before exercise,immediately after exercise,exercise 5 min and 10 min after liver mean value of Young’s modulus(Emean),minimum(Emin)and maximum(Emax),observe the effects of changes in body position and exercise on the Young’s modulus of the liver.Results: There were difference in Young’s modulus of the liver in different positions,and the measured values(Emean,Emin,Emax)in the left supine position were all higher than that in the supine position,with significant difference(P < 0.05),and the measured values of Emean in the supine position were more stable than those in the left supine position.The measured values of Young’s modulus of liver immediately after exercise were all higher than those before exercise,5min after exercise and 10 min after exercise,with significant difference(P < 0.05).There was no significant difference between the measured values before exercise and 5min after exercise(P > 0.05).There was no significant difference between Emean before exercise and Emean 10 min after exercise(P > 0.05),and the Emin and Emax had significant difference(P < 0.05).There was no significant difference of Emean and Emax between 5min and 10 min after exercise(P > 0.05),and the difference of Emin was statistically significant(P < 0.05).The mean value of Young’s modulus of the liver returned to the baseline level 5min after exercise,but the measured value was not as stable as that of the liver 10 min after exercise,with a large degree of dispersion.Conclusion: Changes in body position and exercise have impact on the measurement of the Young’s modulus of the liver,so it is recommended to choose supine position and rest at least 10 min after exercise,which is of great value for normative application of RT-SWE and providing more accurate liver hardness values for clinic.