Analysis Of Associated Risk Factors Of Pulmonary Infection In Postoperative Patients With Hypertensive Basal Ganglia Hemorrhage

Objective: To explore benefit or risk factors of postoperative pulmonary infection in postoperative patients with hypertensive basal ganglia hemorrhage(HBGH).Methods: Retrospectively analyze the clinical data of 228 patients who underwent craniotomy hematoma removal due to HBGH admitted to Cangzhou Central Hospital and Cangzhou people’s hospital from January 1,2018 to December 31,2018.The patients were divided into pulmonary infection group and non-pulmonary infection group according to whether there was postoperative pulmonary infection.The following information was collected: demographic characteristics(age,gender,Body mass index(BMI)),Glasgow Coma Scale on admission(GCS),diabetes,coronary Heart disease,laboratory data on admission(platelet,hemoglobin,blood glucose,serum sodium,serum potassium,activated clotting time live enzymes,plasma fibrinogen,international standardization ratio,plasma prothrombin time,blood plasma thrombin time),perioperative data(preoperative heart rate,mean arterial pressure,anesthesia time,infusion volume of colloid,crystalloid,blood loss,urine,red blood cell infusion,plasma infusion),length of stay,Glasgow Outcome Scale(GOS)after 1 year,time of mechanical ventilation,and whether tracheotomy was performed.The collected data were statistically analyzed using SPSS24.0 software,and the statistically significant indicators in the univariate analysis were included in the multivariate Logistic regression analysis to analyze the independent risk factors and benefit factors of postoperative pulmonary infection patients with HBGH.P < 0.05 was considered statistically significant.Results:1.After the exclusion of the criteria,a total of 170 postoperative patients with HBGH were included in this retrospective study.Among them,121 patients developed pulmonary infection,with an infection rate of 71.6%,and thirteen patients died,with an overall mortality rate of 7.6%.2.Univariate analysis showed that age,GCS score,blood glucose,preoperative heart rate >100 times/min,time of mechanical ventilation,and tracheotomy had statistically significant effects on postoperative pulmonary infection(P<0.05).3.Multivariate Logistic regression analysis showed: increased age(OR=1.087,95%CI=1.038-1.138,P<0.001),decreased GCS score(OR=0.809,95%CI =0.709-0.922,P=0.002),preoperative heart rate >100 times/min(OR=5.032,95%CI=1.682-15.055,P=0.004),prolonged time of mechanical ventilation(OR=1.856,95%CI =1.003-3.433),P=0.049)were independent risk factors for pulmonary infection in postoperative patients with HGBH.Conclusion:1.This study found that increased age,decreased preoperative GCS score,prolonged mechanical ventilation time,and preoperative heart rate of >100 / score were independent risk factors for pulmonary infection in postoperative patients with HGBH.2.For postoperative patients with HGBH,high age,low preoperative GCS score and preoperative heart rate >100 times/score indicate that patients have a high risk of pulmonary infection and relevant prevention work should be done.At the same time,in clinical work,if the patient’s blood oxygen content meets the needs of the body,the use of ventilator should be suspended as soon as possible.