| Objectives Using blood oxygen level-dependent magnetic resonance brain functional imaging(BOLD-f MRI)technology,to observe and analyze the differences in the activation site,volume,and intensity characteristics of proprioceptive centers of patients with cerebral infarction with proprioceptive impairment and healthy volunteers.The distribution and functional changes of proprioceptive centers provide a basis for clinical treatment and rehabilitation of patients with acute infarction with proprioceptive disorders,thereby improving the treatment effect and improving the prognosis of patients.Methods Ten patients with acute phase of cerebral infarction with proprioceptive impairment were included in the experimental group,and 10 healthy volunteers were used as the control group.All subjects were examined and evaluated for relevant clinical indicators,and whole brain BOLD-f MRI scans were performed under Neuro Care-C electromyographic current stimulation of the tibial nerve,and post-processing was performed using software such as SPM12.The positions of the brain function images corresponding to the activated clusters,Volume and intensity,SPSS17.0 was used to perform rank sum test and T test between groups and within groups.Results 1 In the control group,BA4 area(primary motor cortex),BA6/8 area(front motor cortex/auxiliary motor area),BA5/7 area(somatosensory combined cortex),BA3/2 area(somatosensory cortex),BA9/10/11 area(Prefrontal cortex),BA13(island leaf),BA17(primary visual cortex),BA18/19(visual combined cortex),subparietal lobe BA40(secondary somatosensory cortex),middle temporal gyrus BA21,temporal BA22 area in the previous time,BA32 area in the anterior cingulate band of the marginal lobe,BA38 area in the superior temporal gyrus,BA45 and 47 areas in the subfrontal gyrus,cerebellum,beanshaped nuclei,putamen and thalamus are activated.2 In addition to the above parts,the activated brain functional sites in the case group also include brain regions such as the cingulate cortex and para hippocampus(P<0.05).3 In the control group,the volume of activation of the left cerebral hemisphere when stimulating the left tibial nerve in normal adult subjects was not statistically different from the volume of the right cerebral hemisphere(P>0.05),and the LI value was 6.00%.The volume of the right cerebral hemisphere activated when stimulating the right tibial nerve of the subject was not statistically different from the left cerebral hemisphere(P>0.05),and its LI value was-10.95%.In the case group,the volume of the left cerebral hemisphere when the healthy tibial nerve was stimulated in patients with acute cerebral infarction was smaller than that of the right cerebral hemisphere(P=0.00),and its LI value was-24.89%.When the patients with acute cerebral infarction stimulated the lateral tibial nerve,the activated volume of the left cerebral hemisphere was smaller than that of the right cerebral hemisphere(P=0.00),and the LI value was-20.24%.Conclusions 1 Activated proprioceptive-related brain function sites in the control group are mainly located in the central posterior gyrus,auxiliary motor area SAM,supermarginal gyrus SMG,transverse temporal gyrus,anterior wedge lobe,islet,and cerebellum.The part also includes the cingulate cortex and the hippocampal gyrus.Compared with the control group,patients with acute cerebral infarction had multiple changes in brain regions,indicating the existence of compensatory reorganization of brain function.And the brain regions such as the marginal lobe may be the compensated brain regions for proprioceptive function.These abnormal features of brain function may provide new ideas for clinical treatment,evaluation of treatment effect and improvement of prognosis in patients with acute stage of cerebral infarction.2 Right hemisphere laterality exists in the proprioceptive regulation center.Reduced SMG function in the right hemisphere may be related to decreased proprioception.Therefore,it is recommended that clinicians pay special attention to the evaluation and rehabilitation of proprioception after right hemisphere injury.Figure 16;Table 12;Reference 78... |
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