| Objective: To investigate the clinical significance of changes in plasma levels of D-dimer,NT-Pro BNP and inflammatory markers in elderly patients with community acquired pneumonia(CAP).Methods: 76 cases of senile(aged ≥65 years)community-acquired pneumonia admitted to the department of respiratory medicine of the Fourth Affiliated Hospital of China Medical University from January 2018 to January 2019 were selected.Plasma levels of D-D,NT-Pro BNP,PCT,hs-CRP and WBC were measured on admission,and PSI scores were completed after admission.According to the diagnostic criteria of severe pneumonia,the patients were divided into severe pneumonia group and non-severe pneumonia group.The differences in plasma D-D,NT-Pro BNP,PCT,hs-CRP and WBC were compared among the groups,and the correlation between PSI score and D-D,NT-Pro BNP,PCT and hs-CRP was analyzed.Results: There were significant differences in D-D and NT-Pro BNP between the severe pneumonia group and the non-severe pneumonia group(P<0.05),and the indexes of the severe pneumonia group were significantly higher than that of the non-severe pneumonia group.There was a significant difference in inflammatory indexes hs-CRP and PCT between the two groups(P<0.05),the severe pneumonia group was significantly higher than the control group,while the WBC comparison was not significant(P>0.05).PSI score was positively correlated with D-D,NT-Pro BNP,hs-CRP and PCT levels(P<0.01),among which D-D and NT-Pro BNP were strongly correlated.Conclusion: 1.In the elderly patients with CAP,D-D,NT-Pro BNP,hs-CRP and PCT levels were higher in the severe pneumonia group than in the non-severe pneumonia group.2.Elevated levels of D-D,NT-Pro BNP,hs-CRP and PCT suggest severe pneumonia in elderly patients with CAP.3.Changes in D-D,NT-Pro BNP,hs-CRP and PCT levels are of important value in the early evaluation of the severity of community-acquired pneumonia in the elderly and have clinical significance. |
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