| Objective:To investigate the level of vitamin A and vitamin E in full-term pregnant women(≥37 weeks)before delivery,analyze the related factors and the relationship between them and pregnancy outcome,and provide basis for reasonable nutritional guidance for pregnant women.Methods:A study was conducted among eligible pregnant women who received routine pregnancy care in the obstetric outpatient department of our hospital from January 1,2018,to March 31,2019,and delivered in our hospital,the height,weight,age,vitamin A,vitamin E levels,gestational weeks(corrected according to the last menstrual period and ultrasound examination in early pregnancy),the incidence of pregnancy complications,pregnancy outcome(premature rupture of membranes,fetal weight,etc.)were collected.To calculate the long-term BMI,pregnant women were divided into four groups according to BMI: Weight Loss Group(Bm I< 18.5 kg/m2),normal weight group(18.5 kg/m2≤ BMI < 24 kg /m2),overweight group(24 kg/m2≤ BMI < 28 kg/m2)and obese group(BMI ≥28 kg/m2),according to the age of delivery,the pregnant and lying-in women were divided into three groups: the Older Group(≥35 years old)and the appropriate age group(< 35 years old).The content of vitamin A and vitamin E in peripheral blood of full-term pregnant women(≥37 weeks)was measured by High-performance liquid chromatography method,and vitamin A,e content of different and pregnancy outcomes and pregnancy complications may exist in the relationship.Results:(1)In this study,vitamin A concentration(0.392 ±0.11 mg/L),vitamin A abnormality is mainly lack,lack of 202 people,deficiency rate 17.49%.The concentration of vitamin E(14.69 ±5.06 mg/L),the abnormality of vitamin E was mainly excessive,with an excess rate of 12.47%.(2)The maternal BMI in the elderly group(≥ 35 years old)was higher than that in other age groups,and the menopause time in the elderly group was lower than that in the other age groups(P < 0.05).(3)The vitamin A concentration of pregnant women(≥ 35 years old)was higher than that of other age groups(P < 0.11mg/L),and the vitamin E concentration of pregnant women(≥ 35 years old)(15.87 ±5.14mg/L)was higher than that of the 34-year-old group(14.67 ±5.15mg/L)and that of the 26-year-old group(13.44 ±4.25 mg/L),P < 0.05),and the vitamin E concentration of the pregnant women of the older age group(≥ 35 years old)was higher than that of the 34-year-old group(14.67 ±0.05).(4)Age and BMI are the influencing factors of vitamin A concentration,and age is the influencing factors of vitamin E concentration;(5)The serum vitamin A concentration of full-term pregnant women in obesity group was the highest,which was significantly higher than that in other groups(P < 0.11mg/L),and the birth weight of normal weight group(3126.92 ±356.80g)was significantly lower than that of other weight groups(P < 0.05).(6)The BMI of pregnant women in vitamin A deficiency group was different from that in vitamin A normal group,vitamin A deficiency and vitamin E excess were not the risk factors of gestational diabetes,macrosomia,low birth weight and premature rupture of membranes,but the concentration of vitamin A and vitamin E were the influencing factors of neonatal weight.Conclusion:(1)Vitamin A deficiency is the main abnormality of vitamin A in the investigated population,it is recommended to supplement vitamin A intake during pregnancy,and vitamin E abnormality is mainly excessive,which should be supplemented reasonably.(2)The concentration of vitamin A during pregnancy is affected by maternal age and BMI,and vitamin E is affected by maternal age.It is necessary to monitor regularly during pregnancy and formulate individual nutritional recipes according to the conditions of pregnant women to avoid abnormal vitamin A and vitamin E;(3)Vitamin A deficiency and vitamin E excess are not the influencing factors of PROM,gestational diabetes mellitus,macrosomia and low weight infants. |
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