To Research The Effect Of ERAS In The Perioperative Period Of Laparoscopic Radical Gastrectomy For Gastric Cancer

Background and ObjectiveGastric cancer(GC)is a malignant tumor with a high incidence and a high lethality.The current treatment is mainly surgery,which brings severe trauma to the patient while treating the disease,and various complications are prone to occur after surgery,which makes the recovery time of the patient long.In this context,the concept of enhanced recovery after surgery(ERAS)was proposed to promote the recovery rate of patients and shorten the recovery process through various perioperative optimization management schemes.In recent years,it has been widely explored and applied in the professional fields of gynecology,orthopedics,and urology.In recent years,minimally invasive surgery has received more and more attention.Laparoscopic surgery has been actively promoted and developed in medical institutions at all levels due to its low trauma and short recovery time.Although surgical techniques and medical devices have made great progress,there is still some controversy in the application of the concept of rapid rehabilitation surgery in gastric cancer surgery because of the high risk of complications in gastric cancer surgery,and there is less research and abdominal cavity.Mirror surgery combined.This study comprehensively explored the effects of ERAS on the perioperative period of laparoscopic gastric cancer by comprehensively affecting the patient’s recovery time,body inflammation level and nutritional status,and provided theoretical support for promoting the application of ERAS in gastric cancer surgery.MethodA retrospective analysis of 68 patients who underwent laparoscopic radical gastrectomy for gastric cancer in the General Surgery of the Second Affiliated Hospital of Zhengzhou University from October 2017 to September 2019.They were divided into the ERAS group and the control group according to the perioperative management scheme 34 cases.Record the following clinical parameters:general information such as age,gender,BMI(Body Mass Index),TNM staging,and compare the first postoperative exhaust time,postoperative oral feeding time,drainage tube removal time,postoperative hospitalization time,and complications between the two groups,NRS score,C-reactive protein(CRP)and neutrophil percentage(NEUT%),albumin(ALB),and prealbumin(PAB)values before and after surgery.Result(1)There was no significant difference between the two groups of patients in terms of age,gender,and other surgical-related indicators such as surgical method and TNM stage(P>0.05).(2)Compared with the recovery of the two groups,the drainage time of various drainage tubes(gastric tube,abdominal drainage tube)in the ERAS group,the first postoperative feeding time,the first postoperative anal exhaust time,and the postoperative hospital stay were significantly reduced.The difference was statistically significant(P<0.05).(3)Comparing the incidence of postoperative complications between the two groups of patients,5 cases in the ERAS group were lower than 8 cases in the control group,and the difference was not statistically significant(P>0.05).(4)Compared with the postoperative NRS pain score,the ERAS group was generally lower than the control group,and the difference was statistically significant on the first day after surgery(P<0.05).(5)Comparison of nutritional indicators between the two groups,the overall level of ALB in the ERAS group was higher than that in the control group.The postoperative day 1 and postoperative day 3 were higher than those in the control group,the difference was statistically significant(P<0.05);the PAB level in the ERAS group was generally higher than that in the control group,and the PAB value was significantly higher on the first postoperative day.In the control group(P<0.05).(6)Comparison of inflammation indicators,the overall levels of CRP and NEUT%in the ERAS group were lower than those in the control group.Compared with the control group,the CRP values of the ERAS group on the 1st,3rd,and 6th days were significantly different(P<0.05);the NEUT%on the 3rd day after the ERAS group was significantly lower than that of the control group(P<0.05).Conclusion(1)The application of ERAS in the perioperative period of laparoscopic gastric cancer radical surgery can shorten the recovery time of patients without increasing complications;(2)the application of ERAS in the perioperative period of laparoscopic gastric cancer radical surgery can reduce the postoperative inflammatory response and improve the nutritional status,and deserves widespread promotion in the clinic.