The Relationship Between Glycosylated Hemoglobin(HbA1c) And Severity Of Coronary Artery Disease In Patients With Acute ST-segment Elevation Myocardial Infarction Without Diabetes

Objective: To investigate the relationship between glycosylated hemoglobin(HbA1c)and severity of coronary artery disease in patients with acute ST-segment elevation myocardial infarction without diabetes.Methods: From January 2016 to June2017,a total of 251 patients who had no diabetes and were diagnosed with acute ST-segment elevation myocardial infarction were enrolled in the Heart Center of the First Affiliated Hospital of Xinjiang Medical University.The general information and laboratory were recorded.All subjects were divided into 2 groups according to HbA1 c level,A group(HbA1c <5.7%),B group(5.7%≤HbA1c <6.5%),analysis of the factors that affecting the severity of coronary artery stenosis.Results:(1)The BNP,hypertension,creatinine,Gensini score,single stenosis,double stenosis and three-vessel were statistically significant(P<0.05)between two groups;(2)In the glycated hemoglobin B group,the glycated hemoglobin value was correlated with coronary artery disease count and Gensini score: r> 0 and p was significant,so the glycated hemoglobin B group was positively correlated with coronary artery disease count and Gensini score.(3)Logistic regression analysis of the influencing factors of coronary artery branch count showed that the higher the HbA1 c,the higher the Gensini score,and the more coronary artery lesions,the HbA1 c level was correlated with the severity of coronary artery disease;Conclusion:HbA1c is an independent risk factor for severity of coronary arteries stenosis in patients with acute ST-segment elevation myocardial infarction without diabetes.