Study On Differentiation Of Stages Of Colorectal Adenoma Based On Cancer Pathogenesis Theory

Objective:To analyze the number,size,location,and pathological distribution of colorectal adenomas,and to summarize the effects of age,sex,past history,family history,and history of habits on the development of colorectal adenomas.The distribution of TCM syndromes and syndrome types in patients with colorectal adenoma seeks to provide a clinical basis for the point of view of the theory of pathogenesis of cancer to differentiate and treat colorectal adenoma.Research methods:By filling in a questionnaire for clinical symptoms of colorectal adenoma patients,collecting basic information and medical history of patients,using Excel software to build a database of clinical information of colorectal adenoma patients,and applying SPSS 26.0 software to statistics and analyze the database information.Research result:1.The age of colorectal adenoma patients ranges from 27 to 70 years,with an average age of(56.42 ± 9.03)years,and 51-70 years is the high-risk age group for colorectal adenoma patients.2.The incidence of colorectal adenoma in male population is higher than that in female population,and the gender difference of colorectal adenoma patients in different age groups is statistically significant.3.The most common past history of colorectal adenoma patients is hyperlipidemia,the most common family history is colorectal cancer,and the most common lifestyle habits are smoking history and drinking history.4.Smoking history and drinking history are the most common lifestyle habits of male colorectal adenoma patients.Hyperlipidemia and hypertension are the most common past history of middle-aged and elderly patients.5.Male patients with colorectal adenoma have more adenomas than female patients.Middle-aged and elderly patients have more colorectal adenomas than young patients.6.Colorectal adenomas with a diameter of 1.1 cm-1.5cm are the most common,and adenomas with a diameter of more than 2.0cm are the rarest.Colorectal adenomas are not affected by gender and age.Adenomas with a diameter of 0.5 cm and below are common in elderly patients;adenomas with a diameter of>2 cm are common in male patients.7.The sigmoid colon is the best place for adenomas in the entire colon and rectum.Colorectal adenomas are not affected by gender and age.However,hepatic curvature adenomas are more common in male patients.8.Low-grade intraepithelial neoplasia is the most common pathological grade of colorectal adenoma,and the pathological type of colorectal tumor is not affected by the gender and age of patients,but high-grade intraepithelial neoplasia is more common in elderly patients.9.Drinking history is a more common influencing factor for low-grade intraepithelial neoplasia.Family history of hypertension and colorectal cancer are more common influencing factors for high-grade intraepithelial neoplasia.10.Tubular adenoma is the most common pathological type of colorectal adenoma,while villous adenoma is the rarest type,and the colorectal tumor pathological type is not affected by the sex and age of the patient.11.Tubular adenoma is the most common pathological type of low-grade intraepithelial neoplasia,and tubular-villous adenoma and villous adenoma are the most important pathological types of high-grade intraepithelial neoplasia.12.The main TCM clinical symptoms of colorectal adenoma patients are faint abdominal pain,abdominal tingling,diarrhea in the stool,dullness,thin stools,dull complexion,sticky and uncomfortable stool,tired body,and dark stool.Blood in the stool.13.The most common symptoms of colorectal adenoma patients are abdominal symptoms,followed by changes in stool characteristics.14.Wet phlegm and blood stasis syndrome and wet phlegm and blood stasis syndrome are the most important TCM syndromes of colorectal adenoma.15.The patients with damp heat syndrome and intestinal stagnation syndrome are mainly young patients,the patients with damp phlegm and blood stasis syndrome are mainly middle-aged and elderly patients,and the patients with damp phlegm and blood stasis syndrome have no obvious age trend,young,middle-aged and elderly All patients can occur,which is the most important type of TCM syndrome of colorectal adenoma.16.The main pathological type of adenoma in patients with damp phlegm and blood stasis syndrome is tubular adenoma,while the pathological type of patients with wet phlegm and blood stasis syndrome is mainly tubular-villous adenoma.17.The 10 most frequently occurring symptoms of patients with colorectal adenoma with damp phlegm and blood stasis syndrome are abdominal pain faintly,loose stools,dull complexion,dysphoria,sticky and unpleasant stools,heavy limb fatigue,dark purple lips,Black stools,tingling in the abdomen,thin stools.18.The 10 most frequently occurring symptoms of patients with colorectal adenoma wet phlegm and stasis syndrome are abdominal tingling,black stools,heavy weight,tiredness,loose stools,numbness,abdominal pain,faint,dull complexion,stool The lower part is sticky,the stool is thin,and the lips are dark purple.19.The classification criteria for early wet phlegm and blood stasis syndrome of colorectal adenoma are:abdominal pain is faint,lumpy,numb,loose stools or sticky unpleasant stools,but can also see dull complexion,heavy body fatigue and dark lips,Light red tongue,greasy white fur,slippery pulse.20.Colorectal adenoma late wet phlegm and blood stasis syndrome syndrome classification criteria are:abdominal tingling,epilepsy,dullness,dark stool,loose stool,can also see heavy limb fatigue,dull complexion and dark purple lips,The tongue is dark red,with thin fur and fine pulse.Research conclusions:The probability of colorectal adenoma in men is significantly higher than that in women,and the peak age of onset is 51-70 years.The most common history of bad lifestyle habits in patients with colorectal adenoma is a history of smoking and drinking.The most common past history is hyperlipidemia,and the most common family history is colorectal cancer.The sigmoid colon is the best adenoma in the entire colon and rectum,and colorectal adenomas with a diameter of 1.1 cm to 1.5 cm are the most common.Low-grade intraepithelial neoplasia is the most common pathological grade of colorectal adenoma,and tubular adenoma is the most common pathological type.The most common TCM symptoms of colorectal adenoma patients are abdominal symptoms,followed by changes in stool characteristics,and the most common TCM syndromes of colorectal adenoma are wet phlegm and blood stasis syndrome.Colorectal adenoma early wet phlegm and blood stasis syndrome differentiation criteria are:faint abdominal pain,absent-mindedness,loose stools or sticky unpleasant stools,but also can see dull complexion,heavy limb fatigue and dark purple lips,tongue Light red,greasy white fur,slippery pulse.The classification criteria for the syndrome of wet phlegm and blood stasis in the late stage of colorectal adenoma are:tingling in the abdomen,numbness in the stomach,dark stools,and loose stools.Dark red,thin fur,fine pulse.