Clinical Study Of Early-stage Therapeutic Effect Of Ultrasound-guided Radiofrequency Ablation In The Treatment Of Benign Thyroid Nodules

Objective:To evaluate the efficacy and safety of ultrasound-guided radiofrequency ablation(RFA)for benign thyroid nodules.Method:We selected 54 patients(79 benign nodules)with complete inclusion criteria from September 2017 to October 2018 in our hospital.The routine ultrasound examination was performed at 3 months,6 months,and 12 months after operation,and the following indicators were recorded,including observation of lesion changes,calculation of nodule volume reduction rate,and blood supply changes.Five routine thyroid function was performed 3 months after surgery.Results:In this study,a total of 79 benign nodules in 54 patients underwent ultrasound-guided RFA.After 3 months,6 months,and 12 months,the average diameter of the nodules gradually decreased,respectively:(1.86±1.04)cm,(1.55±0.99)cm and(1.30±0.99)cm,the difference was statistically significant(P<0.05).The volume of postoperative nodules gradually decreased,and the average volume was(6.327±9.921)cm~3,(4.356±8.548)cm~3和(3.215±6.985)cm~3,and there was statistically differencebetween them(P<0.05).The mean volume reduction rates before and after surgery were:45.927%,54.330%,70.934%,the difference in the volume reduction rate of nodules was statistically significant(P<0.05),and the rate of solid capsule change was significantly higher than that of solid.Fifty-four patients underwent reexamination of thyroid function at 3 months after operation,and the change was not significant before surgery.The difference was not statistically significant(P>0.05).Of the total of 79 nodules in 54 patients,9(11.39%)were cured,60(75.95%)were markedly effective,4(5.06%)were effective,and 6(7.59%)were ineffective.The total effective rate of this group was 92.41%.During the study,except for a few patients with pain,temporary hoarseness and infection in the operation area,no serious complications such as bleeding,tracheal injury and esophageal injury occurred.Conclusion:Ultrasound-guided radiofrequency ablation for the treatment of benign thyroid nodules is effective,safe,complications,no surgical scars,and can be used as a routine treatment.