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Clinical Observation Of Zhishi Xibai Guizhi Decoction Modified In The Angina After PCI Operation(Phlegm And Blood-Stasis Syndrome)

Posted on:2021-05-29Degree:MasterType:Thesis
Country:ChinaCandidate:Y J WuFull Text:PDF
GTID:2404330602460118Subject:Internal medicine of traditional Chinese medicine
Abstract/Summary:PDF Full Text Request
Objective:To treat patients with the angina after PCI operation(phlegm and blood-stasis syndrome)after PCI,apply Zhishi Xiebai Guizhi Decoction Modified to observe the TCM syndrome score,Seattle angina scale score,angina syndrome score,electrocardiogram,etc.The clinical efficacy of high-sensitivity C-reactive protein and serum nitric oxide to provide an effective TCM treatment plan.Methods;The experiment was conducted according to the random parallel control method.A total of 63 patients with angina pectoris and phlegm-stasis syndrome who were admitted to the ward of Changzhou Traditional Chinese Medicine Hospital from April 2019 to January 2020 and met the case criteria were included.The cases were numbered according to the order of inclusion,and the odd numbers were included in the control.Groups,even numbers are included in the experimental group,32 in the control group and 31 in the experimental group.In this study,32 patients in the control group were treated with conventional Western medicine.The conventional Western medicine treatment was based on the recommended Western traditional basic treatment and the "Coronary Heart Disease" recommended in the "Chinese Medicine Diagnosis and Treatment Program for Stroke Heartache(Angina Pectoris after Coronary Heart Disease and Reconstruction)"prepared by the State Administration of Management.The treatment of microvascular angina pectoris in the Guidelines for Reasonable Medications(Second Edition)is planned.31 patients in the experimental group were added with Zhishi Xiebai Guizhi Decoction Modified(group:Zhishi 10g,Xiebai lOg Gui)lOg sticks,whole melon 10g,magnolia 10g,ginseng 5g,whole scorpion 3g,panax notoginseng 10g).Dosage form:Changzhou Traditional Chinese Medicine Hospital unified decoction decoction.How to take:Take one sachet(150ml)orally every morning and half an hour after lunch.The course of treatment is two weeks.By comparing the changes of TCM syndrome score,Seattle Angina Scale score,electrocardiogram,high-sensitivity C-reactive protein,and serum nitric oxide before and after treatment,the patient’s angina symptom score scale(experimental group and control group)All patients in the group were only taking conventional Western medicines.The effect of Zhishi Xiebai Guizhi Decoction Modified on improving microvascular angina after PCI was studied.Results:After treatment,the experimental group and the control group were improved in terms of TCM syndrome score,Seattle angina score scale,and angina syndrome score before and after treatment,and the experimental group was more significantly improved than the control group,and the difference was statistically significant.In terms of electrocardiogram,both groups can improve the performance of myocardial ischemia on the electrocardiogram,the ST segment depression has increased,and the improvement in the experimental group is more obvious.The difference is statistically significant.In terms of serum nitric oxide,the NO in both groups increased after treatment,and the experimental group was more obvious.The difference was statistically significant.In terms of high-sensitivity C-reactive protein,there was no significant decrease in hs-CRP levels between the two groups before and after treatment,and the difference was not statistically significantConclusion:Patients with angina pectoris after PCI when taking conventional western medicine,the addition of Zhishi Xiebai Guizhi Decoction Modified can alleviate the symptoms of angina pectoris,improve exercise tolerance,increase NO level,improve quality of life and prognosis,and is safe.Good,no obvious adverse reactions.
Keywords/Search Tags:Zhishi Xiebai Guizhi Decoction Modified, Angina After PCI Operation, Phlegm and Blood-atasis Syndrome, Clinincal Observat
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