| Purpose People with hypertension are more likely to have anxiety and depression.Anxiety and depression can also affect the control of blood pressure and the occurrence of hypertension complications in hypertensive patients.This study mainly explores the relationship between anxiety and depression and hypertension;the influence of anxiety and depression on the prevalence of hypertension,blood pressure control rate and hypertension complications;patients with hypertension and anxiety and depression on the basis of antihypertensive drugs Psychological and anxiety depression after drug intervention,the impact on the patient’s blood pressure control rate.Method A total of 272 patients with hypertension and non-hypertensive patients admitted to the Department of Cardiology of Shaanxi Provincial People’s Hospital from April 2017 to August 2018 were enrolled.The generalized anxiety self-rating scale(GAD-7)was used to assess anxiety status and the patient health questionnaire depression self-rating scale(PHQ-9)to assess depression status,and to analyze the relationship between anxiety score and depression score and diastolic blood pressure and systolic blood pressure.The prevalence of anxiety and depression in hypertensive patients and non-hypertensive patients,and multivariate logistic regression analysis of the relationship between anxiety and depression and hypertension.To further investigate the 165 patients with hypertension in the study group,according to whether they were associated with anxiety and depression,the patients were divided into hypertension,anxiety and depression group and simple hypertension group.The differences of blood pressure control rate and hypertension complications were compared between the two groups.The factors affecting hypertension were analyzed by adjusting the confounding factors and using multivariate logistic regression to analyze the effects of anxiety and depression on hypertension complications.Patients with hypertension and anxiety and depression were randomly divided into treatment group and control group according to whether intervention was given.Non-parametric test and chi-square test were used to analyze the difference of anxiety and depression scores and the difference of blood pressure control rate between the two groups before and after intervention.Results1.The mean diastolic blood pressure of 272 patients was 79.18±12.21 mm Hg,the mean systolic blood pressure was 135.12±21.61 mm Hg,the average anxiety score was 6.15±4.27,and the average depression score was 4.44±3.29.The study found that anxiety and depression were associated with systolic blood pressure(P ≤ 0.001),but not with diastolic blood pressure(P > 0.05);the prevalence of anxiety in 165 patients with hypertension was63%,the prevalence of depression 47.9%,the prevalence of anxiety and depression comorbidity was 36.4%;107 cases of non-hypertensive patients,the prevalence of anxiety was 43%,the prevalence of depression was 31.1%,and the prevalence of anxiety and depression comorbidities was 21.5%.Multivariate logistic regression analysis of anxiety-depression and hypertension showed that anxiety,depression and hypertension were significantly associated(P<0.001),anxiety B=0.926,OR=2.524,depression B=1.368,OR=3.926,Depression is more closely related to anxiety and hypertension.2.Hypertension combined with anxiety and depression group compared with simple hypertension group,found that there were significant differences in cervical vascular disease,complicated cerebrovascular disease,blood pressure control compliance rate,hypertension grade,uric acid(UA),triglyceride(TG),etc.(P<0.05);complicated with heart disease,urea nitrogen(UREA),creatinine(CRE),total cholesterol(TC),high-density lipoprotein cholesterol(HDL),low-density lipoprotein cholesterol(LDL),free triiodothyronine There were no significant differences in FT3,free thyroxine(FT4)and thyrotropin(TSH)(P>0.05).After multiple corrections by multivariate logistic regression model,it was found that there was no significant difference in anxiety and depression between hypertension and cervical vascular disease and cerebrovascular disease(P>0.05).3.Compared with the control group and the control group,the anxiety and depression scores were significantly different(P<0.05),and there was a significant difference in the blood pressure control compliance rate between the treatment group and the control group.Statistical significance(P<0.05);the anxiety and depression scores after intervention were significantly lower than before intervention(P<0.001).Conclusion1.Anxiety and depression are associated with hypertension and are mainly related to systolic blood pressure.Anxiety and depression are independent risk factors for hypertension,and the effect of depression on hypertension is more obvious.2.Hypertension combined with anxiety and depression is more likely to fail blood pressure control;anxiety and depression have no significant effect on cervical vascular complications and cerebrovascular complications of hypertension.3.After psychological and drug intervention in patients with hypertension and anxiety and depression,the anxiety and depression scores decreased and the blood pressure control compliance rate increased significantly. |