The Investigation On The Related Factors Of Osteoporotic Fracture In The Han Postmenopausal Women In Dalian

Objective: To investigate the related factors of osteoporotic fracture in the Han postmenopausal women in Dalian and to provide the reference to prevent and reduce the occurrence of osteoporotic fracture.Methods: A total of 439 the Han postmenopausal women with osteoporotic fracture in Dalian who applied for the chronic disease subsidy of "severe osteoporosis combined with osteoporotic fracture" in 2018 were selected as the survey objects.Collected Relevant data by on-site questionnaire survey and then made statistical analysis.Results:1.The average number of osteoporotic fracture time was 1.71 and the average number of osteoporotic fracture site was 2.51.Vertebral fracture,distal forearm fracture,hip fracture and proximal humerus fracture was 84.74%,20.27%,11.16% and 6.61%.The first vertebral fracture,distal forearm fracture,hip fracture and proximal humerus fracture was73.55%16.63%,7.52% and 3.64%.2.The awareness rate of the first osteoporotic fracture was 21.64%,and 192 cases(43.74%)didn’t receive any treatment after the first osteoporotic fracture.3.There were already some osteoporotic fractures in the 50 to 59 age group,accounting for 6.83% of the total.Among them,vertebral fracture was the most common(83.33%),the average number of vertebral fracture time was 1.20,and the average number of vertebral fracture site was 2.12.Vertebral fracture was the most common in all age groups,and the difference was statistically significant compared with other fracture groups(all P<0.05).Hip fracture was significantly increasing over 80 years old,and the difference was statistically significant compared with the 50 to 59 years old group(P<0.05).4.There were already some osteoporotic fractures occurred during perimenopausal period and within 5 years after menopause,accounting for 5.69% and 6.15% of the total,and vertebral fracture was the most common in the two groups(69.57% and 66.67%).The incidence of osteoporotic fracture within 10 years after menopause was similar to thatwithin 5 years after menopause,and there was no statistically significant difference in the incidence of vertebral fracture,distal forearm fracture and hip fracture compared with that within 5 years after menopause(all P>0.05).5.Compared with the group without family history of brittle fracture,the age of first osteoporotic fracture in the group with family history of brittle fracture was lower(all P<0.05).The number of fracture time and site was more,and the bone density of femoral neck was lower,but the differences were not statistically significant(all P>0.05).The mean BMD of lumbar 1-4 in the group with brittle fracture in both parents was lower,and the difference was statistically significant(P<0.05).Compared with the group with brittle fracture in the mother and the group with brittle fracture in the father,the age of the first osteoporotic fracture was younger,the number of fracture time and site was more,and the BMD was lower,but there were no statistics differences(all P>0.05).6.The lean group accounted for 7.06% of the total,among which vertebral fracture was the most common(74.19%),hip fracture was the second(29.03%).The overweight group accounted for 12.07%,vertebral fracture was the most common(88.68%),distal forearm fracture was the second(18.87%).Compared with the normal BMI group,hip fracture was increasing significantly in the lean group with statistically significant difference(P<0.05),while there were no statistically significant differences in the other three fractures(all P>0.05).In the overweight group,vertebral fracture was increasing and hip fracture was decreasing,but the differences were not statistically significant(all P>0.05).7.Compared with the group without type 2 diabetes,the age of the first osteoporotic fracture in the group with type 2 diabetes was younger,the number of fracture time and site was more,and the BMD was lower,but the differences were not statistically significant(all P>0.05).8.In this investigation,73.91% of the patients were untreated after the first osteoporotic vertebral fracture.Among them,33.33% suffered vertebral fracture within 1 year after the fist fracture and most of them suffered vertebral fracture more than 3 years(49.02%).9.Correlation analysis showed that with the increasing of age,the number of fracture time and site was increasing(all P<0.05).BMI and BMD had no significant effect on the number of fracture time or site(all P>0.05).Conclusion:1.In this investigation,there were already some osteoporotic fractures occurred during perimenopausal period and within 5 years after menopause.It is suggested that we should pay more attention to the screening,prevention and treatment of osteoporosis and osteoporotic fracture in order to delay or reduce the occurrence of osteoporosis and osteoporotic fracture.2.In this investigation,the awareness rate of osteoporosis was very low when osteoporotic fracture occurred,the anti-osteoporosis treatment rate was even lower,the treatment standardization was poor,and the reoccurrence rate of fractures was high.It is suggested that the propaganda and education of prevention and treatment of osteoporosis should be strengthened,and the standardization of clinical treatment should be improved.