Study On The Influence Of Stent Inserting On Coronary Bifurcation Side Branch

Coronary stent as an important method in the treatment of coronary bifurcation lesions has been widely used in clinic.But in the actual clinical operations,because of the complexity of the situation,some problems may occur in a certain extent,such as postoperative side branch vessel distortion and blood flow change.These will also cause certain influence on blood perfusion of side branch vessel and the effect of interventional therap.The purpose of this research is that explore the influence of side branch vessel during the coronary stent insert the coronary artery bifurcation vessel by using the method of finite element analysis,in order to provide theoretical reference for clinical doctor.The research contents are as follows:1.The influence of coronary stent inserting different plaque situation coronary stenosis bifurcation vessel on side branch vessel.Coronary stent model and different plaque situation coronary stenosis bifurcation vessel ideal models are built to simulate the process from the coronary stent unassembled state to the inserting coronary stenosis bifurcation vessel service status.Then,analyzing the influence of coronary stent inserting on side branch vessel stress and morphology.In addition,blood flow analysis of side branch vessel after coronary stent inserting coronary stenosis bifurcation vessel is conducted to investigate the influence of coronary stent inserting the coronary stenosis bifurcation vessel on side branch vessel blood flow.2.Establishment coronary stent inserting personalized coronary stenosis bifurcation vessel model.The patient coronary artery CT image is used to build the coronary stenosis bifurcation vessel personalized model with independent vessel and plaque.Then,matching the model with coronary stent.The results showed that: during the process of coronary stent insert different plaque situation bifurcation vessels,first,the stress and morphological of side branch vessel changed most pronounced at the moment of the coronary stent inflated to the largest position.Second,with the increase of plaque stenosis degree,the stress and morphological of side branch vessel changed more obvious.With the increase of plaque length or the increase of distance form bifurcation to plaque,the stress change and deformation of side branch vessel decreased.In addition,compared with the different plaque length model and different plaque location model,the change of stress and morphological on side branch vessel were more obvious in different plaque stenosis degree model,during the process of coronary stent insert bifurcation vessel.In the analysis of blood flow change in branch coronary artery after the coronary stent inserting coronary stenosis bifurcation vessel,irregular flow field distribution appeared near the bifurcation site of branch vessels after the coronary stent inserting,the blood flow of side branch vessel was reduced at the same time.In the matching between coronary stent and coronary stenosis bifurcation vessel personalized model,the change was reasonable of coronary stent stress and shape,also it was nicely matched between coronary stent and bifurcation vessel lumen.Getting the following conclusion from the above results:1.During the process of coronary stent inserted coronary stenosis bifurcation vessel,the changes in stress and morphology are two main performance of the influence on the side branch vessel.And the influence is most significant at the moment of coronary stent inflated to the largest position.Then,it is more likely to have a greater influence on side branch vessel in the process of coronary stent inserting larger stenosis plaque,shorter length plaque,and closer distance plaque coronary stenosis bifurcation vessel.In addition,comparing with plaque length and plaque location,the influence on side branch vessel of plaque stenosis degree is more obvious.Therefore,clinicians should pay more attention when dealing with the above-mentioned conditions.2.During the process of coronary stent inserting the bifurcation vessel,the changes of the flow field distribution and the decrease in blood flow are two main performance of the influence on the side branch vessel.These will affect the downstream blood supply to some extent.3.Coronary stent inserting personalized coronary stenosis bifurcation vessel model to lay the foundation for futher study on the influence of stent inserting on coronary bifurcation side branch.Finite element analysis is used to explore the influence of coronary stent inserting coronary stenosis bifurcation vessel of different plaque situation on side branch vessel,it provides a certain theoretical reference for clinicians.Coronary stent inserting personalized coronary stenosis bifurcation vessel model is build to lay the foundation for the following study.