| Objective: To explore the factors affecting the endoscopic gastric transit time,small bowel transit time and the completion rate of whole small intestine examination of small intestine capsule.Methods: 907 patients who met the indications of capsule endoscopy and underwent OMOM capsule endoscopy in Digestive Endoscopy Center of The General Hospital of Western Theater Command from July 2008 to December 2018 were retrospectively analyzed.Relevant information of patients was collected and analyzed statistically in two parts.The first part: The subjects with intestinal tract preparation methods in the collected data are grouped according to intestinal tract preparation drugs,and the basic conditions of the subjects between the groups are statistically analyzed,and whether there are differences in gastric transit time,intestinal transit time,examination completion rate and intestinal lesion detection rate between the two groups are discussed respectively;Part II: Ignore the influencing factors of intestinal preparation drugs,discuss the influence of different clinical characteristics of the subjects on gastrointestinal transit time,discuss the influence of different intestinal lesions detected on intestinal transit time,and discuss the influencing factors of intestinal examination completion rate by single factor and multi-factor analysis.Statistical analysis of all data was carried out by SPSS 17.0 software,and the difference was statistically significant when P < 0.05.Results:(1)644 patients with intestinal preparation drugs were divided into compound polyethylene glycol electrolyte powder group(523 cases)and 20% mannitol group(121 cases)according to the intestinal preparation drugs used.there was no significant difference in gastrointestinal transit time between groups(P> 0.05),but the detection rate of intestinal lesions in 20% mannitol group was significantly higher than that in compound polyethylene glycol electrolyte powder group(P=0.021).(2)The gastric transit time of hospitalized patients was significantly longer than that of outpatients(P=0.042).(3)The transit time of small bowel was significantly prolonged in males,subjects aged ≥ 60 years old and patients with small intestinal lesions(P < 0.01),and small intestinal ulcer was a risk factor for the prolongation of transit time of small intestine.(4)Prolonged transit time of male and gastrointestinal tract is a risk factor for incomplete examination of whole small intestine.(5)12 patients had capsule endoscope retention of small intestine(retention rate was 1.3%),of which 2 patients took out capsule endoscope after abdominal surgery.48 patients were sent into duodenum by capsule endoscopy,33 of them(68.8%)completed the examination of the whole small intestine,and 31 cases(64.6%)were found pathological changes.(6)In this study,all the subjects were well tolerated and there were no complications caused by capsule endoscopy.Conclusion:(1)In this study,there is no significant difference in the effect of compound polyethylene glycol electrolyte powder or 20% mannitol on gastrointestinal transit time and completion rate of whole small intestine examination,but preoperative administration of 20% mannitol significantly improves the detection rate of small intestine lesions.It is suggested that 20% mannitol be used for intestinal preparation before capsule endoscopy examination.(2)Real-time monitoring of hospitalized patients.If capsule endoscopy stays in the stomach for more than 30 min,then intervention is considered.(3)Medical personnel should monitor the patients aged ≥ 60 years old,male patients and patients clinically suspected of small intestinal hemorrhage or small intestinal ulcer in real time.When it is found that their small intestine is pushed slowly,relevant effective driving measures should be actively taken to speed up small bowel transit time,thus increasing the completion rate of whole small intestine examination.(4)In this study,the prolongation of gastrointestinal transit time and men are the risk factors that the whole small intestine examination cannot be completed.(5)Endoscopic delivery of capsule endoscopy into duodenum is a safe and effective method to shorten gastric transit time. |
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