Difference Study Of Risk Factors And Coronary Arterial Lesions In Different Genders And Ages Of Patients With Acute Myocardial Infarction

Objective: To analyze the differences and regional characteristics of risk factors and coronary arterial lesion characteristics in patients with acute myocardial infarction(AMI)of different genders and age groups in Qingdao,to provide a theoretical basis for targeted prevention and individualized medical intervention.Methods: 1050 patients with AMI were collected from three districts of Qingdao University Affiliated Hospital(Shinan district,Laoshan district and Huangdao west coast new district)from January to October 2017.The patients were divided into two groups according to gender,including 865 male patients and 219 female patients,or were divided into four groups according to age,consisting of < 50 years(n=124),50~59(n=199),60~69(n=330),and ≥ 70 years(n=397).Statistical analysis and difference comparison were performed on the risk factors and the characteristics of coronary artery lesions in different genders and age groups.Result: The average onset age of male AMI patients was younger than that of females((62.01 ± 12.35)vs(71.43 ± 9.75),P < 0.01).Overall,the proportion of smoking patients and the body mass index(BMI)of patients showed a downward trend with the increase of age,while the proportion of female patients gradually increased,which was statistically significant(P < 0.01).The proportion of AMI patients with hypertension increased first and then decreased with age,the highest proportion was in the 60~69 age group(62.4%).The proportion of male patients with hypertension was higher than that of females(54.9% vs 46.1%,P < 0.05).The proportion of patients with diabetes increased with age and the proportion of women with AMI and diabetes was higher than that of men(40.3% vs 23.9%,P < 0.01).After the age of 60,the proportion of women with diabetes in all age groups was higher than that of men,especially in patients with ST-segment elevation myocardial infarction(STEMI),and the proportion of women with diabetes was up to 55.6% in the 50-59 age group.With the increase of age,triacylglycerol(TG)levels gradually decreased,however high-density lipoprotein(HDL-C)levels gradually increased.Coronary angiography results showed that with the increase of age,the proportion of single vessel disease in AMI patients was gradually decreased(P < 0.01).In addition,the rate of patients < 50 years who had a single vascular disease was as high as 50.9%,and they were most commonly diagnosed with LAD lesions.Last but not least,the patients who suffered from multivessel disease gradually increasd,with a 76.9% proportion of patients > 70 years old and LAD,right coronary artery(RCA)lesions were more common.Conclusion: There were unique regional features of risk factors and coronary arterial lesion characteristics in patients with acute myocardial infarction(AMI)of different genders and age groups in Qingdao.The proportion of patients with hypertension increased first and then decreased with age,the proportion of patients with diabetes increased with age,female STEMI patients more than half of the 50~59 age group had diabetes.It was noticeable that the proportion of single-vessel disease in patients <50 years old was greater than 50%.The results provided epidemiological evidence for formulating individualized and regional prevention measures for people in Qingdao.