| Objectives To evaluate the therapeutic effect of Yinge Zhixie Powder in treating autumn diarrhea in children with damp-heat type and compared with Montmorillonite Powder.Methods All the patients were selected from the paediatric ward of the first Chinese Medicine Hospital of Baoding City(October 2017 to December 2018).72 children aged between 6 months and 3 years old who met the inclusion criteria of wet heat type infantile autumn diarrhea were selected.According to the random number table method,the experiment was carried out in 36 cases in the test group(Yinge Zhixie powder group)and36 cases in the control group(montmorillonite powder group).The course of treatment was5 days.According to the classification and quantification of TCM syndromes and signs,the distribution of time of stopping diarrhea,the total clinical effective rate,the rate of RV turning negative,and the safety,etc.To observe and evaluate the clinical effect of the two groups before and after treatment.Results Statistical analysis was carried out with SPSS20.0 software system.Results 1 The sex,age,weight,course of disease,condition,symptoms and signs of the two groups were statistically analyzed(P>0.05).There was no statistical difference,and they were comparable.2 In the two groups of children,the clinical effect level distribution and the total effective rate of clinical efficacy,the treatment group recovered 21 cases(51%),markedly effective 9 cases(31%),effective 3 cases(11%),and 2 cases were ineffective(6%),the total effective rate was 94.29%.The control group was cured in 13cases(29%),markedly effective in 6 cases(34%),effective in 8 cases(17%),and ineffective in 8 cases(20%).The total effective rate is 77.14%.The clinical efficacy grade distribution and total curative effect of the treatment group were statistically different compared with the control group(P<0.05).3 In the two groups,the cumulative number of patients after treatment for 1d,2d,3d,4d,and 5d was 8 cases,14 cases,19 cases,23 cases,26 cases.The control group was 2 cases,6 cases,13 cases,19 cases,and 21 cases.In the two groups,the time between the two groups was significantly different(P<0.05)after treatment for 1 day and 2 days after treatment.After 3 days of treatment,4 days later,5days later,the children of the two groups were treated.There was no significant difference in diarrhea time(P>0.05).4 Comparison of symptoms and signs before and after treatment between the two groups showed that the effect of changing the number of defecation was similar(P>0.05).There was a statistical difference between the two groups in improving defecation traits,abdominal distension,non-dairy food,nausea and vomiting,mental distress,fever,short yellow urine,red anus,tongue coating and fingerprint(P<0.05).5Compared with the control group,the experimental group was lower than the total score of the TCM syndrome(P<0.05).Compared with the total integral of TCM syndrome before and after treatment,the effect of treatment was significant(P<0.05).6 In the two groups of children before and after treatment changes in RV,the treatment group’s negative rate was80.00%,and the control group’s negative rate was 57.14%.There was a statistically significant difference between the two groups(P<0.05).7 One case was lost in each group because the children did not cooperate with the treatment.No adverse clinical events occurred.There were no significant differences in liver and kidney function tests between the two groups before and after treatment(P>0.05).Conclusions 1 Yinge Zhixie Powder is effective in the treatment of damp-heat infantile autumn diarrhea.The overall curative effect was better than that of montmorillonite powder group.2 Yinge Zhixie Powder could obviously improve the symptoms of children,and shorten the time of stopping diarrhea within 2 days.It has significant effect on improving defecation,abdominal distension,not thinking milk food,nausea and vomiting,mental distress,fever,short yellow urine,red anus,tongue coating,fingerprint,increasing RV negative rate,and no obvious adverse reaction.Figure0;Table12;Reference 109... |
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