Efficacy Analysis Of Nasal Bi-level Positive Airway Pressure Ventilation And Nasal Continuous Positive Airway Pressure Ventilation In The Treatment Of Neonatal Respiratory Distress Syndrome

Objectivecomparison of nasal bi-level positive airway pressure ventilation and nasal continuous positive airway pressure ventilation in the treatment of neonatal respiratory distress syndrome.MethodsA retrospective analysis was performed on 129 preterm infants with neonatal respiratory distress syndrome who were admitted to the neonatal intensive care unit of Union Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology between January,2017 and February,2019.According to the non-invasive respiratory support model,they were divided into NBiPAP group?n=68?and NCPAP group?n=61?.The general conditions,high risk factors,blood gas changes,inhaled oxygen concentration,invasive respiratory support time,non-invasive respiratory support time,total oxygen consumption time,hospital stay,and complications were compared between the two groups.ResultsThere were significant differences in PH,PCO₂ and FiO₂ of the two groups before and after treatment?P<0.05?.The PH at 6 and 12 hours and the PCO₂ at 6 hours after treatment of NBiPAP group were better than those in NCPAP group,and the difference between the two groups was statistically significant?P<0.05?.The proportion of invasive respiratory support required in the NBiPAP group was lower than that in the NCPAP group,and the difference between the two groups was statistically significant?P<0.05?.There were no significant differences in the invasive respiratory support time,non-invasive respiratory support time,total oxygen consumption time,hospital stay and complications between the two groups?P>0.05?.ConclusionNBiPAP and NCPAP are effective in the treatment of neonatal respiratory distress syndrome.Compared with NCPAP,NBiPAP can reduce the invasive respiratory support rate without increasing the incidence of complications.