Correlation Between First Diagnosis Of Lung CT And Laboratory Examination And Survival After 3 Years Of Paraquat Poisoning

Objective: Retrospective analysis of the relationship between CT findings and laboratory-related examinations(both within 12 hours after taking the drug)in patients with acute paraquat poisoning(APP)and postsurvival status.Methods: The A total of 179 patients with acute paraquat poisoning were enrolled in the Emergency Department of the second Hospital of Hebei Medical University in 2014.The 76 patients with paraquat(Paraquat PQ)poisoning who survived at discharge were excluded from the standard and returned by telephone three years later.Retrospective analysis of 76 cases of paralyzed patients with parasitic CT scan data and laboratory-related examination values(both within 12 hours after taking the drug),according to the patient’s survival after three years,were divided into survival group and death group.Among them,the survival group(59 cases)and the death group(17 cases)recorded and analyzed the results of chest CT examination and laboratory related examinations within 12 hours after admission,the laboratory related examinations including: Neutrophil percentage(NP),Lymphocyte percentage(LP),Alanine Transaminase(ALT),blood glucose.Using SPSS21.0 software,single-factor logistic regression analysis was performed on lung CT findings.Laboratory-related examinations were performed by t-test,expressed as mean±standard deviation.Multivariate logistic regression analysis was used for indicators with statistically significant differences and finding the independent risk factors affecting 3-year survival.P < 0.05 indicates significant statistical differences.Results:1.Chest CT findings: 1 increased lung texture,20 patients in the survival group(26.3%),5 patients in the death group(29.4%);2 lung grinding glass density(GGO),survival group 20(26.3%),death group 5 cases(29.4%)3 atelectasis,0 cases in survival group,3 cases(17.6%)in death group;4 subpleural line,survival group,29 cases(38.1%),and death group(65.2%);Pleural thickening,survival group 20(26.3%),death group 7(41.1%);6 pleural effusion,survival group 11(14.5%),death group 6(35.2%);7 pericardial effusion,survival 1 case(0.1%),4 cases(23.5%)in the death group;8 mediastinal emphysema,0 cases in the survival group,and 3 cases(17.6%)in the death group.2.In the single-factor logistic regression analysis of chest CT findings,atelectasis,mediastinal emphysema,and pericardial effusion were statistically different between the survival group and the death group.There was no statistically significant difference in other performances.3.In the laboratory-related examination,there was a statistically significant difference in the percentage of neutrophils(NP),percentage of lymphocytes(LP),and blood glucose(BG)between the survival group and the death group;There was no statistical difference in alanine aminotransferase(ALT)between the two groups.4.Multivariate logistic regression analysis showed that there were significant differences in atelectasis,percentage of lymphocytes(LP)and blood glucose(BG)between the two groups.Conclusion: PQ poisoning(within 12h)first-time lung CT and laboratory-related indicators have objective clinical guiding value for predicting 3-year survival;atelectasis,percentage of lymphocytes,and blood glucose are independent risk factors for survival after 3 years.